Donald Coen, PhD

Professor of Biological Chemistry and Molecular Pharmacology, Harvard Medical School
Maternal immunization confers protection against neonatal herpes simplex mortality and behavioral morbidity.
Authors: Authors: Patel CD, Backes IM, Taylor SA, Jiang Y, Marchant A, Pesola JM, Coen DM, Knipe DM, Ackerman ME, Leib DA.
Sci Transl Med
View full abstract on Pubmed
Unexpected features and mechanism of heterodimer formation of a herpesvirus nuclear egress complex.
Authors: Authors: Lye MF, Sharma M, El Omari K, Filman DJ, Schuermann JP, Hogle JM, Coen DM.
EMBO J
View full abstract on Pubmed
Net -1 frameshifting on a noncanonical sequence in a herpes simplex virus drug-resistant mutant is stimulated by nonstop mRNA.
Authors: Authors: Pan D, Coen DM.
Proc Natl Acad Sci U S A
View full abstract on Pubmed
Priscilla Schaffer (1941-2009): a stalwart herpesvirologist.
Authors: Authors: Coen D.
J Virol
View full abstract on Pubmed
The positively charged surface of herpes simplex virus UL42 mediates DNA binding.
Authors: Authors: Komazin-Meredith G, Santos WL, Filman DJ, Hogle JM, Verdine GL, Coen DM.
J Biol Chem
View full abstract on Pubmed
Herpesviral latency-associated transcript gene promotes assembly of heterochromatin on viral lytic-gene promoters in latent infection.
Authors: Authors: Wang QY, Zhou C, Johnson KE, Colgrove RC, Coen DM, Knipe DM.
Proc Natl Acad Sci U S A
View full abstract on Pubmed
Translational compensation of a frameshift mutation affecting herpes simplex virus thymidine kinase is sufficient to permit reactivation from latency.
Authors: Authors: Griffiths A, Chen SH, Horsburgh BC, Coen DM.
J Virol
View full abstract on Pubmed
Enzymatic amplification of DNA by PCR: standard procedures and optimization.
Authors: Authors: Kramer MF, Coen DM.
Curr Protoc Immunol
View full abstract on Pubmed
white+ transgene insertions presenting a dorsal/ventral pattern define a single cluster of homeobox genes that is silenced by the polycomb-group proteins in Drosophila melanogaster.
Authors: Authors: Netter S, Fauvarque MO, Diez del Corral R, Dura JM, Coen D.
Genetics
View full abstract on Pubmed
Mutations that specifically impair the DNA binding activity of the herpes simplex virus protein UL42.
Authors: Authors: Chow CS, Coen DM.
J Virol
View full abstract on Pubmed