Donald Coen, PhD

Professor of Biological Chemistry and Molecular Pharmacology, Harvard Medical School
Synergistic effects on ganglionic herpes simplex virus infections by mutations or drugs that inhibit the viral polymerase and thymidine kinase.
Authors: Authors: Jacobson J, Kramer M, Rozenberg F, Hu A, Coen DM.
Virology
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A point mutation in the human cytomegalovirus DNA polymerase gene confers resistance to ganciclovir and phosphonylmethoxyalkyl derivatives.
Authors: Authors: Sullivan V, Biron KK, Talarico C, Stanat SC, Davis M, Pozzi LM, Coen DM.
Antimicrob Agents Chemother
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P element regulatory products enhance zeste repression of a P[white duplicated] transgene in Drosophila melanogaster.
Authors: Authors: Coen D.
Genetics
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Immediate-early regulatory gene mutants define different stages in the establishment and reactivation of herpes simplex virus latency.
Authors: Authors: Leib DA, Coen DM, Bogard CL, Hicks KA, Yager DR, Knipe DM, Tyler KL, Schaffer PA.
J Virol
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Herpes simplex virus mutants resistant to arabinosyladenine in the presence of deoxycoformycin.
Authors: Authors: Fleming HE, Coen DM.
Antimicrob Agents Chemother
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Mitochondrial genetics. XI. Mutations at the mitochondrial locus omega affecting the recombination of mitochondrial genes in Saccharomyces cerevisiae.
Authors: Authors: Dujon B, Bolotin-Fukuhara M, Coen D, Deutsch J, Netter P, Slonimski PP, Weill L.
Mol Gen Genet
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Viral Ubiquitin Ligase Stimulates Selective Host MicroRNA Expression by Targeting ZEB Transcriptional Repressors.
Authors: Authors: Lutz G, Jurak I, Kim ET, Kim JY, Hackenberg M, Leader A, Stoller ML, Fekete DM, Weitzman MD, Coen DM, Wilson AC.
Viruses
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HIV integrase inhibitors block replication of alpha-, beta-, and gammaherpesviruses.
Authors: Authors: Yan Z, Bryant KF, Gregory SM, Angelova M, Dreyfus DH, Zhao XZ, Coen DM, Burke TR, Knipe DM.
MBio
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Human cytomegalovirus UL44 concentrates at the periphery of replication compartments, the site of viral DNA synthesis.
Authors: Authors: Strang BL, Boulant S, Chang L, Knipe DM, Kirchhausen T, Coen DM.
J Virol
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Mutations that increase DNA binding by the processivity factor of herpes simplex virus affect virus production and DNA replication fidelity.
Authors: Authors: Jiang C, Komazin-Meredith G, Tian W, Coen DM, Hwang CB.
J Virol
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