Donald Coen, PhD

Professor of Biological Chemistry and Molecular Pharmacology, Harvard Medical School
Functional analysis of the herpes simplex virus UL42 protein.
Authors: Authors: Digard P, Chow CS, Pirrit L, Coen DM.
J Virol
View full abstract on Pubmed
Engineered herpes simplex virus DNA polymerase point mutants: the most highly conserved region shared among alpha-like DNA polymerases is involved in substrate recognition.
Authors: Authors: Marcy AI, Hwang CB, Ruffner KL, Coen DM.
J Virol
View full abstract on Pubmed
Thymidine kinase-negative herpes simplex virus mutants establish latency in mouse trigeminal ganglia but do not reactivate.
Authors: Authors: Coen DM, Kosz-Vnenchak M, Jacobson JG, Leib DA, Bogard CL, Schaffer PA, Tyler KL, Knipe DM.
Proc Natl Acad Sci U S A
View full abstract on Pubmed
Alternate utilization of two regulatory domains within the Moloney murine sarcoma virus long terminal repeat.
Authors: Authors: Graves BJ, Eisenberg SP, Coen DM, McKnight SL.
Mol Cell Biol
View full abstract on Pubmed
Maize chloroplast DNA fragment encoding the large subunit of ribulosebisphosphate carboxylase.
Authors: Authors: Coen DM, Bedbrook JR, Bogorad L, Rich A.
Proc Natl Acad Sci U S A
View full abstract on Pubmed
Herpes Simplex Virus 1 DNA Polymerase RNase H Activity Acts in a 3'-to-5' Direction and Is Dependent on the 3'-to-5' Exonuclease Active Site.
Authors: Authors: Lawler JL, Mukherjee P, Coen DM.
J Virol
View full abstract on Pubmed
Human cytomegalovirus UL97 phosphorylates the viral nuclear egress complex.
Authors: Authors: Sharma M, Bender BJ, Kamil JP, Lye MF, Pesola JM, Reim NI, Hogle JM, Coen DM.
J Virol
View full abstract on Pubmed
Host cell nucleolin is required to maintain the architecture of human cytomegalovirus replication compartments.
Authors: Authors: Strang BL, Boulant S, Kirchhausen T, Coen DM.
MBio
View full abstract on Pubmed
The crystal structure of PF-8, the DNA polymerase accessory subunit from Kaposi's sarcoma-associated herpesvirus.
Authors: Authors: Baltz JL, Filman DJ, Ciustea M, Silverman JE, Lautenschlager CL, Coen DM, Ricciardi RP, Hogle JM.
J Virol
View full abstract on Pubmed
Binding parameters and thermodynamics of the interaction of the human cytomegalovirus DNA polymerase accessory protein, UL44, with DNA: implications for the processivity mechanism.
Authors: Authors: Loregian A, Sinigalia E, Mercorelli B, Palù G, Coen DM.
Nucleic Acids Res
View full abstract on Pubmed