Donald Coen, PhD

Professor of Biological Chemistry and Molecular Pharmacology, Harvard Medical School
Reduction and elimination of encephalitis in an experimental glioma therapy model with attenuated herpes simplex mutants that retain susceptibility to acyclovir.
Authors: Authors: Markert JM, Malick A, Coen DM, Martuza RL.
Neurosurgery
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Herpes simplex virus transactivator ICP4 operationally substitutes for the cellular transcription factor Sp1 for efficient expression of the viral thymidine kinase gene.
Authors: Authors: Imbalzano AN, Coen DM, DeLuca NA.
J Virol
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A deletion mutant of the latency-associated transcript of herpes simplex virus type 1 reactivates from the latent state with reduced frequency.
Authors: Authors: Leib DA, Bogard CL, Kosz-Vnenchak M, Hicks KA, Coen DM, Knipe DM, Schaffer PA.
J Virol
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Promoter domains required for expression of plasmid-borne copies of the herpes simplex virus thymidine kinase gene in virus-infected mouse fibroblasts and microinjected frog oocytes.
Authors: Authors: Eisenberg SP, Coen DM, McKnight SL.
Mol Cell Biol
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Maize plastid gene expressed during photoregulated development.
Authors: Authors: Bedbrook JR, Link G, Coen DM, Bogorad L.
Proc Natl Acad Sci U S A
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A Role for Myosin Va in Human Cytomegalovirus Nuclear Egress.
Authors: Authors: Wilkie AR, Sharma M, Pesola JM, Ericsson M, Fernandez R, Coen DM.
J Virol
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Mechanism of ganciclovir-induced chain termination revealed by resistant viral polymerase mutants with reduced exonuclease activity.
Authors: Authors: Chen H, Beardsley GP, Coen DM.
Proc Natl Acad Sci U S A
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Herpes simplex virus is equipped with RNA- and protein-based mechanisms to repress expression of ATRX, an effector of intrinsic immunity.
Authors: Authors: Jurak I, Silverstein LB, Sharma M, Coen DM.
J Virol
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Nucleolin associates with the human cytomegalovirus DNA polymerase accessory subunit UL44 and is necessary for efficient viral replication.
Authors: Authors: Strang BL, Boulant S, Coen DM.
J Virol
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Human cytomegalovirus protein kinase UL97 forms a complex with the tegument phosphoprotein pp65.
Authors: Authors: Kamil JP, Coen DM.
J Virol
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