Donald Coen, PhD

Professor of Biological Chemistry and Molecular Pharmacology, Harvard Medical School
Engineered herpes simplex virus DNA polymerase point mutants: the most highly conserved region shared among alpha-like DNA polymerases is involved in substrate recognition.
Authors: Authors: Marcy AI, Hwang CB, Ruffner KL, Coen DM.
J Virol
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Thymidine kinase-negative herpes simplex virus mutants establish latency in mouse trigeminal ganglia but do not reactivate.
Authors: Authors: Coen DM, Kosz-Vnenchak M, Jacobson JG, Leib DA, Bogard CL, Schaffer PA, Tyler KL, Knipe DM.
Proc Natl Acad Sci U S A
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Alternate utilization of two regulatory domains within the Moloney murine sarcoma virus long terminal repeat.
Authors: Authors: Graves BJ, Eisenberg SP, Coen DM, McKnight SL.
Mol Cell Biol
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Maize chloroplast DNA fragment encoding the large subunit of ribulosebisphosphate carboxylase.
Authors: Authors: Coen DM, Bedbrook JR, Bogorad L, Rich A.
Proc Natl Acad Sci U S A
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A Role for Myosin Va in Human Cytomegalovirus Nuclear Egress.
Authors: Authors: Wilkie AR, Sharma M, Pesola JM, Ericsson M, Fernandez R, Coen DM.
J Virol
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Mechanism of ganciclovir-induced chain termination revealed by resistant viral polymerase mutants with reduced exonuclease activity.
Authors: Authors: Chen H, Beardsley GP, Coen DM.
Proc Natl Acad Sci U S A
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Herpes simplex virus is equipped with RNA- and protein-based mechanisms to repress expression of ATRX, an effector of intrinsic immunity.
Authors: Authors: Jurak I, Silverstein LB, Sharma M, Coen DM.
J Virol
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Nucleolin associates with the human cytomegalovirus DNA polymerase accessory subunit UL44 and is necessary for efficient viral replication.
Authors: Authors: Strang BL, Boulant S, Coen DM.
J Virol
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Human cytomegalovirus protein kinase UL97 forms a complex with the tegument phosphoprotein pp65.
Authors: Authors: Kamil JP, Coen DM.
J Virol
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An unusual internal ribosome entry site in the herpes simplex virus thymidine kinase gene.
Authors: Authors: Griffiths A, Coen DM.
Proc Natl Acad Sci U S A
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