Donald Coen, PhD
Professor of Biological Chemistry and Molecular Pharmacology, Harvard Medical School
Acyclovir-resistant, pathogenic herpesviruses.
Expanded spectrum of viral therapy in the treatment of nervous system tumors.
Authors: Authors: Markert JM, Coen DM, Malick A, Mineta T, Martuza RL.
J Neurosurg
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J Neurosurg
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A novel functional domain of an alpha-like DNA polymerase. The binding site on the herpes simplex virus polymerase for the viral UL42 protein.
Low levels of herpes simplex virus thymidine- thymidylate kinase are not limiting for sensitivity to certain antiviral drugs or for latency in a mouse model.
Generation of genetic diversity in herpes simplex virus: an antimutator phenotype maps to the DNA polymerase locus.
Authors: Authors: Hall JD, Coen DM, Fisher BL, Weisslitz M, Randall S, Almy RE, Gelep PT, Schaffer PA.
Virology
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Virology
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Mitochondrial genetics. VI. The petite mutation in Saccharomyces cerevisiae: interrelations between the loss of the p+ factor and the loss of the drug resistance mitochondrial genetic markers.
Authors: Authors: Deutsch J, Dujon B, Netter P, Petrochilo E, Slonimski PP, Bolotin-Fukuhara M, Coen D.
Genetics
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Genetics
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Getting to and through the inner nuclear membrane during herpesvirus nuclear egress.
Authors: Authors: Lye MF, Wilkie AR, Filman DJ, Hogle JM, Coen DM.
Curr Opin Cell Biol
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Curr Opin Cell Biol
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Comparison of effects of inhibitors of viral and cellular protein kinases on human cytomegalovirus disruption of nuclear lamina and nuclear egress.
Antiviral drugs and antiviral drug resistance.
Analysis of the association of the human cytomegalovirus DNA polymerase subunit UL44 with the viral DNA replication factor UL84.
Authors: Authors: Strang BL, Sinigalia E, Silva LA, Coen DM, Loregian A.
J Virol
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J Virol
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