Donald Coen, PhD
Professor of Biological Chemistry and Molecular Pharmacology, Harvard Medical School
Mutations that specifically impair the DNA binding activity of the herpes simplex virus protein UL42.
Evidence for a novel regulatory pathway for herpes simplex virus gene expression in trigeminal ganglion neurons.
Authors: Authors: Kosz-Vnenchak M, Jacobson J, Coen DM, Knipe DM.
J Virol
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J Virol
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The implications of resistance to antiviral agents for herpesvirus drug targets and drug therapy.
Examination of the roles of transcription factor Sp1-binding sites and an octamer motif in trans induction of the herpes simplex virus thymidine kinase gene.
Sequence and mapping analyses of the herpes simplex virus DNA polymerase gene predict a C-terminal substrate binding domain.
Authors: Authors: Gibbs JS, Chiou HC, Hall JD, Mount DW, Retondo MJ, Weller SK, Coen DM.
Proc Natl Acad Sci U S A
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Proc Natl Acad Sci U S A
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Differential expression of the gene for the large subunit of ribulose bisphosphate carboxylase in maize leaf cell types.
Herpes Simplex Virus 1 Lytic Infection Blocks MicroRNA (miRNA) Biogenesis at the Stage of Nuclear Export of Pre-miRNAs.
Authors: Authors: Pan D, Li G, Morris-Love J, Qi S, Feng L, Mertens ME, Jurak I, Knipe DM, Coen DM.
MBio
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MBio
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Preparation of the Human Cytomegalovirus Nuclear Egress Complex and Associated Proteins.
The pre-NH(2)-terminal domain of the herpes simplex virus 1 DNA polymerase catalytic subunit is required for efficient viral replication.
Interaction of the human cytomegalovirus uracil DNA glycosylase UL114 with the viral DNA polymerase catalytic subunit UL54.