Donald Coen, PhD
Professor of Biological Chemistry and Molecular Pharmacology, Harvard Medical School
ICP27 selectively regulates the cytoplasmic localization of a subset of viral transcripts in herpes simplex virus type 1-infected cells.
Linear diffusion on DNA despite high-affinity binding by a DNA polymerase processivity factor.
ND10 protein PML is recruited to herpes simplex virus type 1 prereplicative sites and replication compartments in the presence of viral DNA polymerase.
Wheel keeps turning for antiviral combination chemotherapy.
CNS tumor therapy by attenuated herpes simplex viruses.
Authors: Authors: Mineta T, Markert JM, Takamiya Y, Coen DM, Rabkin SD, Martuza RL.
Gene Ther
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Gene Ther
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Isolation of foscarnet-resistant human cytomegalovirus patterns of resistance and sensitivity to other antiviral drugs.
Enzymatic activities of overexpressed herpes simplex virus DNA polymerase purified from recombinant baculovirus-infected insect cells.
Authors: Authors: Marcy AI, Olivo PD, Challberg MD, Coen DM.
Nucleic Acids Res
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Nucleic Acids Res
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General aspects of virus drug resistance with special reference to herpes simplex virus.
Mutations in the herpes simplex virus DNA polymerase gene can confer resistance to 9-beta-D-arabinofuranosyladenine.
Potency and Stereoselectivity of Cyclopropavir Triphosphate Action on Human Cytomegalovirus DNA Polymerase.
Authors: Authors: Chen H, Li C, Zemlicka J, Gentry BG, Bowlin TL, Coen DM.
Antimicrob Agents Chemother
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Antimicrob Agents Chemother
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