Donald Coen, PhD

Professor of Biological Chemistry and Molecular Pharmacology, Harvard Medical School
Inactivation of retinoblastoma protein does not overcome the requirement for human cytomegalovirus UL97 in lamina disruption and nuclear egress.
Authors: Authors: Reim NI, Kamil JP, Wang D, Lin A, Sharma M, Ericsson M, Pesola JM, Golan DE, Coen DM.
J Virol
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Inactivation and disassembly of the anaphase-promoting complex during human cytomegalovirus infection is associated with degradation of the APC5 and APC4 subunits and does not require UL97-mediated phosphorylation of Cdh1.
Authors: Authors: Tran K, Kamil JP, Coen DM, Spector DH.
J Virol
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Hopping of a processivity factor on DNA revealed by single-molecule assays of diffusion.
Authors: Authors: Komazin-Meredith G, Mirchev R, Golan DE, van Oijen AM, Coen DM.
Proc Natl Acad Sci U S A
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Selective anti-cytomegalovirus compounds discovered by screening for inhibitors of subunit interactions of the viral polymerase.
Authors: Authors: Loregian A, Coen DM.
Chem Biol
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Failure of thymidine kinase-negative herpes simplex virus to reactivate from latency following efficient establishment.
Authors: Authors: Chen SH, Pearson A, Coen DM, Chen SH.
J Virol
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Enzymatic amplification of DNA by PCR: standard procedures and optimization.
Authors: Authors: Kramer MF, Coen DM.
Curr Protoc Pharmacol
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The role of herpes simplex virus ICP27 in the regulation of UL24 gene expression by differential polyadenylation.
Authors: Authors: Hann LE, Cook WJ, Uprichard SL, Knipe DM, Coen DM.
J Virol
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Antiviral drug resistance in herpes simplex virus.
Authors: Authors: Coen DM.
Adv Exp Med Biol
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The herpes simplex virus type 1 regulatory protein ICP0 enhances virus replication during acute infection and reactivation from latency.
Authors: Authors: Cai W, Astor TL, Liptak LM, Cho C, Coen DM, Schaffer PA.
J Virol
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Polymerization activity of an alpha-like DNA polymerase requires a conserved 3'-5' exonuclease active site.
Authors: Authors: Gibbs JS, Weisshart K, Digard P, deBruynKops A, Knipe DM, Coen DM.
Mol Cell Biol
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