Douglas Melton, PhD

Xander University Professor of Stem Cell and Regenerative Biology, Faculty of Arts & Sciences
A Nutrient-Sensing Transition at Birth Triggers Glucose-Responsive Insulin Secretion.
Authors: Authors: Helman A, Cangelosi AL, Davis JC, Pham Q, Rothman A, Faust AL, Straubhaar JR, Sabatini DM, Melton DA.
Cell Metab
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Apolipoprotein E is a pancreatic extracellular factor that maintains mature ß-cell gene expression.
Authors: Authors: Mahmoud AI, Galdos FX, Dinan KA, Jedrychowski MP, Davis JC, Vujic A, Rachmin I, Shigley C, Pancoast JR, Lee S, Hollister-Lock J, MacGillivray CM, Gygi SP, Melton DA, Weir GC, Lee RT.
PLoS One
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MARIS: method for analyzing RNA following intracellular sorting.
Authors: Authors: Hrvatin S, Deng F, O'Donnell CW, Gifford DK, Melton DA.
PLoS One
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Sox17 promotes differentiation in mouse embryonic stem cells by directly regulating extraembryonic gene expression and indirectly antagonizing self-renewal.
Authors: Authors: Niakan KK, Ji H, Maehr R, Vokes SA, Rodolfa KT, Sherwood RI, Yamaki M, Dimos JT, Chen AE, Melton DA, McMahon AP, Eggan K.
Genes Dev
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All beta cells contribute equally to islet growth and maintenance.
Authors: Authors: Brennand K, Huangfu D, Melton D.
PLoS Biol
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Global expression analysis of gene regulatory pathways during endocrine pancreatic development.
Authors: Authors: Gu G, Wells JM, Dombkowski D, Preffer F, Aronow B, Melton DA.
Development
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Effects of eight growth factors on the differentiation of cells derived from human embryonic stem cells.
Authors: Authors: Schuldiner M, Yanuka O, Itskovitz-Eldor J, Melton DA, Benvenisty N.
Proc Natl Acad Sci U S A
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Short-range signaling by candidate morphogens of the TGF beta family and evidence for a relay mechanism of induction.
Authors: Authors: Reilly KM, Melton DA.
Cell
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Xwnt-11: a maternally expressed Xenopus wnt gene.
Authors: Authors: Ku M, Melton DA.
Development
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The stability, toxicity and effectiveness of unmodified and phosphorothioate antisense oligodeoxynucleotides in Xenopus oocytes and embryos.
Authors: Authors: Woolf TM, Jennings CG, Rebagliati M, Melton DA.
Nucleic Acids Res
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