Douglas Melton, PhD

Xander University Professor of Stem Cell and Regenerative Biology, Faculty of Arts & Sciences
Synchronized stimulation and continuous insulin sensing in a microfluidic human Islet on a Chip designed for scalable manufacturing.
Authors: Authors: Glieberman AL, Pope BD, Zimmerman JF, Liu Q, Ferrier JP, Kenty JHR, Schrell AM, Mukhitov N, Shores KL, Tepole AB, Melton DA, Roper MG, Parker KK.
Lab Chip
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Long-term glycemic control using polymer-encapsulated human stem cell-derived beta cells in immune-competent mice.
Authors: Authors: Vegas AJ, Veiseh O, Gürtler M, Millman JR, Pagliuca FW, Bader AR, Doloff JC, Li J, Chen M, Olejnik K, Tam HH, Jhunjhunwala S, Langan E, Aresta-Dasilva S, Gandham S, McGarrigle JJ, Bochenek MA, Hollister-Lock J, Oberholzer J, Greiner DL, Weir GC, Melton DA, Langer R, Anderson DG.
Nat Med
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New findings in pancreatic and intestinal endocrine development to advance regenerative medicine.
Authors: Authors: Carolan PJ, Melton DA.
Curr Opin Endocrinol Diabetes Obes
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Transcriptional dynamics of endodermal organ formation.
Authors: Authors: Sherwood RI, Chen TY, Melton DA.
Dev Dyn
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Pten constrains centroacinar cell expansion and malignant transformation in the pancreas.
Authors: Authors: Stanger BZ, Stiles B, Lauwers GY, Bardeesy N, Mendoza M, Wang Y, Greenwood A, Cheng KH, McLaughlin M, Brown D, Depinho RA, Wu H, Melton DA, Dor Y.
Cancer Cell
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Role of endothelial cells in early pancreas and liver development.
Authors: Authors: Lammert E, Cleaver O, Melton D.
Mech Dev
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Pancreas development is promoted by cyclopamine, a hedgehog signaling inhibitor.
Authors: Authors: Kim SK, Melton DA.
Proc Natl Acad Sci U S A
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Translational control of activin in Xenopus laevis embryos.
Authors: Authors: Klein PS, Melton DA.
Dev Genet
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Diffusible factors in vertebrate embryonic induction.
Authors: Authors: Jessell TM, Melton DA.
Cell
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The mRNA encoding elongation factor 1-alpha (EF-1 alpha) is a major transcript at the midblastula transition in Xenopus.
Authors: Authors: Krieg PA, Varnum SM, Wormington WM, Melton DA.
Dev Biol
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