Douglas Melton, PhD
Xander University Professor of Stem Cell and Regenerative Biology, Faculty of Arts & Sciences
Inhibition of mTOR Signaling Enhances Maturation of Cardiomyocytes Derived From Human-Induced Pluripotent Stem Cells via p53-Induced Quiescence.
Authors: Authors: Garbern JC, Helman A, Sereda R, Sarikhani M, Ahmed A, Escalante GO, Ogurlu R, Kim SL, Zimmerman JF, Cho A, MacQueen L, Bezzerides VJ, Parker KK, Melton DA, Lee RT.
Circulation
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Circulation
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Reprogrammed Stomach Tissue as a Renewable Source of Functional ß Cells for Blood Glucose Regulation.
Authors: Authors: Ariyachet C, Tovaglieri A, Xiang G, Lu J, Shah MS, Richmond CA, Verbeke C, Melton DA, Stanger BZ, Mooney D, Shivdasani RA, Mahony S, Xia Q, Breault DT, Zhou Q.
Cell Stem Cell
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Cell Stem Cell
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Functional evaluation of ES cell-derived endodermal populations reveals differences between Nodal and Activin A-guided differentiation.
Authors: Authors: Chen AE, Borowiak M, Sherwood RI, Kweudjeu A, Melton DA.
Development
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Development
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Optimal timing of inner cell mass isolation increases the efficiency of human embryonic stem cell derivation and allows generation of sibling cell lines.
Authors: Authors: Chen AE, Egli D, Niakan K, Deng J, Akutsu H, Yamaki M, Cowan C, Fitz-Gerald C, Zhang K, Melton DA, Eggan K.
Cell Stem Cell
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Cell Stem Cell
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Beta-catenin is essential for pancreatic acinar but not islet development.
Genes, signals, and lineages in pancreas development.
Vertebrate endoderm development.
Induction of dorsal mesoderm by soluble, mature Vg1 protein.
Vegetal messenger RNA localization directed by a 340-nt RNA sequence element in Xenopus oocytes.
Bimodal and graded expression of the Xenopus homeobox gene Xhox3 during embryonic development.