Douglas Melton, PhD
Xander University Professor of Stem Cell and Regenerative Biology, Faculty of Arts & Sciences
Midkine is a dual regulator of wound epidermis development and inflammation during the initiation of limb regeneration.
Pancreas regeneration.
Brief report: VGLL4 is a novel regulator of survival in human embryonic stem cells.
Authors: Authors: Tajonar A, Maehr R, Hu G, Sneddon JB, Rivera-Feliciano J, Cohen DE, Elledge SJ, Melton DA.
Stem Cells
View full abstract on Pubmed
Stem Cells
View full abstract on Pubmed
Notch signaling promotes airway mucous metaplasia and inhibits alveolar development.
Authors: Authors: Guseh JS, Bores SA, Stanger BZ, Zhou Q, Anderson WJ, Melton DA, Rajagopal J.
Development
View full abstract on Pubmed
Development
View full abstract on Pubmed
Notch signaling reveals developmental plasticity of Pax4(+) pancreatic endocrine progenitors and shunts them to a duct fate.
Signals from lateral plate mesoderm instruct endoderm toward a pancreatic fate.
Authors: Authors: Kumar M, Jordan N, Melton D, Grapin-Botton A.
Dev Biol
View full abstract on Pubmed
Dev Biol
View full abstract on Pubmed
Hedgehog signals regulate multiple aspects of gastrointestinal development.
Xenopus Mad proteins transduce distinct subsets of signals for the TGF beta superfamily.
Interaction of Wnt and activin in dorsal mesoderm induction in Xenopus.
Signal transduction during mesoderm induction in Xenopus.