Douglas Melton, PhD
Xander University Professor of Stem Cell and Regenerative Biology, Faculty of Arts & Sciences
Identification of a LIF-Responsive, Replication-Competent Subpopulation of Human ß Cells.
Authors: Authors: Rosado-Olivieri EA, Aigha II, Kenty JH, Melton DA.
Cell Metab
View full abstract on Pubmed
Cell Metab
View full abstract on Pubmed
Establishment of human pluripotent stem cell-derived pancreatic ß-like cells in the mouse pancreas.
Authors: Authors: Ma H, Wert KJ, Shvartsman D, Melton DA, Jaenisch R.
Proc Natl Acad Sci U S A
View full abstract on Pubmed
Proc Natl Acad Sci U S A
View full abstract on Pubmed
How to make a functional ß-cell.
Small molecules efficiently direct endodermal differentiation of mouse and human embryonic stem cells.
Authors: Authors: Borowiak M, Maehr R, Chen S, Chen AE, Tang W, Fox JL, Schreiber SL, Melton DA.
Cell Stem Cell
View full abstract on Pubmed
Cell Stem Cell
View full abstract on Pubmed
Reversal of type 1 diabetes in mice.
Endothelial signaling during development.
Early mouse endoderm is patterned by soluble factors from adjacent germ layers.
Induction of axial mesoderm by zDVR-1, the zebrafish orthologue of Xenopus Vg1.
A truncated activin receptor inhibits mesoderm induction and formation of axial structures in Xenopus embryos.
Interaction between peptide growth factors and homoeobox genes in the establishment of antero-posterior polarity in frog embryos.