Douglas Melton, PhD

Xander University Professor of Stem Cell and Regenerative Biology, Faculty of Arts & Sciences
A method for the generation of human stem cell-derived alpha cells.
Authors: Authors: Peterson QP, Veres A, Chen L, Slama MQ, Kenty JHR, Hassoun S, Brown MR, Dou H, Duffy CD, Zhou Q, Matveyenko AV, Tyrberg B, Sörhede-Winzell M, Rorsman P, Melton DA.
Nat Commun
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Blastemal progenitors modulate immune signaling during early limb regeneration.
Authors: Authors: Tsai SL, Baselga-Garriga C, Melton DA.
Development
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Reversal of ß cell de-differentiation by a small molecule inhibitor of the TGFß pathway.
Authors: Authors: Blum B, Roose AN, Barrandon O, Maehr R, Arvanites AC, Davidow LS, Davis JC, Peterson QP, Rubin LL, Melton DA.
Elife
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Turning straw into gold: directing cell fate for regenerative medicine.
Authors: Authors: Cohen DE, Melton D.
Nat Rev Genet
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A multipotent progenitor domain guides pancreatic organogenesis.
Authors: Authors: Zhou Q, Law AC, Rajagopal J, Anderson WJ, Gray PA, Melton DA.
Dev Cell
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Derivation of embryonic stem-cell lines from human blastocysts.
Authors: Authors: Cowan CA, Klimanskaya I, McMahon J, Atienza J, Witmyer J, Zucker JP, Wang S, Morton CC, McMahon AP, Powers D, Melton DA.
N Engl J Med
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Regulation of pancreas development by hedgehog signaling.
Authors: Authors: Hebrok M, Kim SK, St Jacques B, McMahon AP, Melton DA.
Development
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Signals for tissue induction and organ formation in vertebrate embryos.
Authors: Authors: Melton D.
Harvey Lect
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Follistatin, an antagonist of activin, is expressed in the Spemann organizer and displays direct neuralizing activity.
Authors: Authors: Hemmati-Brivanlou A, Kelly OG, Melton DA.
Cell
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A mouse macrophage factor induces head structures and organizes a body axis in Xenopus.
Authors: Authors: Sokol S, Wong GG, Melton DA.
Science
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