Douglas Melton, PhD
Xander University Professor of Stem Cell and Regenerative Biology, Faculty of Arts & Sciences
Xfin: an embryonic gene encoding a multifingered protein in Xenopus.
Exogenous GDF11, but not GDF8, reduces body weight and improves glucose homeostasis in mice.
Authors: Authors: Walker RG, Barrandon O, Poggioli T, Dagdeviren S, Carroll SH, Mills MJ, Mendello KR, Gomez Y, Loffredo FS, Pancoast JR, Macias-Trevino C, Marts C, LeClair KB, Noh HL, Kim T, Banks AS, Kim JK, Cohen DE, Wagers AJ, Melton DA, Lee RT.
Sci Rep
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Sci Rep
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Author Correction: Pancreas regeneration.
Differentiated human stem cells resemble fetal, not adult, ß cells.
Authors: Authors: Hrvatin S, O'Donnell CW, Deng F, Millman JR, Pagliuca FW, DiIorio P, Rezania A, Gifford DK, Melton DA.
Proc Natl Acad Sci U S A
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Proc Natl Acad Sci U S A
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How to make beta cells?
Organ size is limited by the number of embryonic progenitor cells in the pancreas but not the liver.
Notch signaling controls multiple steps of pancreatic differentiation.
Authors: Authors: Murtaugh LC, Stanger BZ, Kwan KM, Melton DA.
Proc Natl Acad Sci U S A
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Proc Natl Acad Sci U S A
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Development of the pancreas in Xenopus laevis.
A molecular mechanism for the effect of lithium on development.
Processed Vg1 protein is an axial mesoderm inducer in Xenopus.