Douglas Melton, PhD
Xander University Professor of Stem Cell and Regenerative Biology, Faculty of Arts & Sciences
Studies with a Xenopus BMP receptor suggest that ventral mesoderm-inducing signals override dorsal signals in vivo.
Authors: Authors: Graff JM, Thies RS, Song JJ, Celeste AJ, Melton DA.
Cell
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Cell
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Pre-existent pattern in Xenopus animal pole cells revealed by induction with activin.
The process of localizing a maternal messenger RNA in Xenopus oocytes.
Generation of hypoimmunogenic human pluripotent stem cells.
Authors: Authors: Han X, Wang M, Duan S, Franco PJ, Kenty JH, Hedrick P, Xia Y, Allen A, Ferreira LMR, Strominger JL, Melton DA, Meissner TB, Cowan CA.
Proc Natl Acad Sci U S A
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Proc Natl Acad Sci U S A
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A Src inhibitor regulates the cell cycle of human pluripotent stem cells and improves directed differentiation.
Authors: Authors: Chetty S, Engquist EN, Mehanna E, Lui KO, Tsankov AM, Melton DA.
J Cell Biol
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J Cell Biol
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Adenosine kinase inhibition selectively promotes rodent and porcine islet ß-cell replication.
Authors: Authors: Annes JP, Ryu JH, Lam K, Carolan PJ, Utz K, Hollister-Lock J, Arvanites AC, Rubin LL, Weir G, Melton DA.
Proc Natl Acad Sci U S A
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Proc Natl Acad Sci U S A
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Wnt7b stimulates embryonic lung growth by coordinately increasing the replication of epithelium and mesenchyme.
Authors: Authors: Rajagopal J, Carroll TJ, Guseh JS, Bores SA, Blank LJ, Anderson WJ, Yu J, Zhou Q, McMahon AP, Melton DA.
Development
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Development
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Altered nuclear transfer in stem-cell research - a flawed proposal.
Direct evidence for the pancreatic lineage: NGN3+ cells are islet progenitors and are distinct from duct progenitors.
Notochord repression of endodermal Sonic hedgehog permits pancreas development.