Douglas Melton, PhD
Xander University Professor of Stem Cell and Regenerative Biology, Faculty of Arts & Sciences
Nuclear reprogramming of somatic cells after fusion with human embryonic stem cells.
Direct lineage tracing reveals the ontogeny of pancreatic cell fates during mouse embryogenesis.
Mixer, a homeobox gene required for endoderm development.
Vertebrate embryonic induction: mesodermal and neural patterning.
Injected Wnt RNA induces a complete body axis in Xenopus embryos.
Involvement of the Xenopus homeobox gene Xhox3 in pattern formation along the anterior-posterior axis.
Charting cellular identity during human in vitro ß-cell differentiation.
Authors: Authors: Veres A, Faust AL, Bushnell HL, Engquist EN, Kenty JH, Harb G, Poh YC, Sintov E, Gürtler M, Pagliuca FW, Peterson QP, Melton DA.
Nature
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Nature
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Angptl4 links a-cell proliferation following glucagon receptor inhibition with adipose tissue triglyceride metabolism.
Authors: Authors: Ben-Zvi D, Barrandon O, Hadley S, Blum B, Peterson QP, Melton DA.
Proc Natl Acad Sci U S A
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Proc Natl Acad Sci U S A
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Functional beta-cell maturation is marked by an increased glucose threshold and by expression of urocortin 3.
Authors: Authors: Blum B, Hrvatin S, Schuetz C, Bonal C, Rezania A, Melton DA.
Nat Biotechnol
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Nat Biotechnol
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Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds.
Authors: Authors: Huangfu D, Maehr R, Guo W, Eijkelenboom A, Snitow M, Chen AE, Melton DA.
Nat Biotechnol
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Nat Biotechnol
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