Douglas Melton, PhD

Xander University Professor of Stem Cell and Regenerative Biology, Faculty of Arts & Sciences
Induction of pluripotent stem cells from primary human fibroblasts with only Oct4 and Sox2.
Authors: Authors: Huangfu D, Osafune K, Maehr R, Guo W, Eijkelenboom A, Chen S, Muhlestein W, Melton DA.
Nat Biotechnol
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Nuclear reprogramming of somatic cells after fusion with human embryonic stem cells.
Authors: Authors: Cowan CA, Atienza J, Melton DA, Eggan K.
Science
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Direct lineage tracing reveals the ontogeny of pancreatic cell fates during mouse embryogenesis.
Authors: Authors: Gu G, Brown JR, Melton DA.
Mech Dev
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Mixer, a homeobox gene required for endoderm development.
Authors: Authors: Henry GL, Melton DA.
Science
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Vertebrate embryonic induction: mesodermal and neural patterning.
Authors: Authors: Kessler DS, Melton DA.
Science
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Injected Wnt RNA induces a complete body axis in Xenopus embryos.
Authors: Authors: Sokol S, Christian JL, Moon RT, Melton DA.
Cell
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The process of localizing a maternal messenger RNA in Xenopus oocytes.
Authors: Authors: Yisraeli JK, Sokol S, Melton DA.
Development
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Charting cellular identity during human in vitro ß-cell differentiation.
Authors: Authors: Veres A, Faust AL, Bushnell HL, Engquist EN, Kenty JH, Harb G, Poh YC, Sintov E, Gürtler M, Pagliuca FW, Peterson QP, Melton DA.
Nature
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Angptl4 links a-cell proliferation following glucagon receptor inhibition with adipose tissue triglyceride metabolism.
Authors: Authors: Ben-Zvi D, Barrandon O, Hadley S, Blum B, Peterson QP, Melton DA.
Proc Natl Acad Sci U S A
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Functional beta-cell maturation is marked by an increased glucose threshold and by expression of urocortin 3.
Authors: Authors: Blum B, Hrvatin S, Schuetz C, Bonal C, Rezania A, Melton DA.
Nat Biotechnol
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