Douglas Melton, PhD
Xander University Professor of Stem Cell and Regenerative Biology, Faculty of Arts & Sciences
Axial patterning and the establishment of polarity in the frog embryo.
A Stem Cell Approach to Cure Type 1 Diabetes.
Pancreas regeneration.
Brief report: VGLL4 is a novel regulator of survival in human embryonic stem cells.
Authors: Authors: Tajonar A, Maehr R, Hu G, Sneddon JB, Rivera-Feliciano J, Cohen DE, Elledge SJ, Melton DA.
Stem Cells
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Stem Cells
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Notch signaling promotes airway mucous metaplasia and inhibits alveolar development.
Authors: Authors: Guseh JS, Bores SA, Stanger BZ, Zhou Q, Anderson WJ, Melton DA, Rajagopal J.
Development
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Development
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Notch signaling reveals developmental plasticity of Pax4(+) pancreatic endocrine progenitors and shunts them to a duct fate.
Signals from lateral plate mesoderm instruct endoderm toward a pancreatic fate.
Authors: Authors: Kumar M, Jordan N, Melton D, Grapin-Botton A.
Dev Biol
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Dev Biol
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Hedgehog signals regulate multiple aspects of gastrointestinal development.
Xenopus Mad proteins transduce distinct subsets of signals for the TGF beta superfamily.
Interaction of Wnt and activin in dorsal mesoderm induction in Xenopus.