Douglas Melton, PhD

Xander University Professor of Stem Cell and Regenerative Biology, Faculty of Arts & Sciences
Signals for tissue induction and organ formation in vertebrate embryos.
Authors: Authors: Melton D.
Harvey Lect
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Follistatin, an antagonist of activin, is expressed in the Spemann organizer and displays direct neuralizing activity.
Authors: Authors: Hemmati-Brivanlou A, Kelly OG, Melton DA.
Cell
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A mouse macrophage factor induces head structures and organizes a body axis in Xenopus.
Authors: Authors: Sokol S, Wong GG, Melton DA.
Science
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A maternal mRNA localized to the vegetal hemisphere in Xenopus eggs codes for a growth factor related to TGF-beta.
Authors: Authors: Weeks DL, Melton DA.
Cell
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A Nutrient-Sensing Transition at Birth Triggers Glucose-Responsive Insulin Secretion.
Authors: Authors: Helman A, Cangelosi AL, Davis JC, Pham Q, Rothman A, Faust AL, Straubhaar JR, Sabatini DM, Melton DA.
Cell Metab
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Apolipoprotein E is a pancreatic extracellular factor that maintains mature ß-cell gene expression.
Authors: Authors: Mahmoud AI, Galdos FX, Dinan KA, Jedrychowski MP, Davis JC, Vujic A, Rachmin I, Shigley C, Pancoast JR, Lee S, Hollister-Lock J, MacGillivray CM, Gygi SP, Melton DA, Weir GC, Lee RT.
PLoS One
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MARIS: method for analyzing RNA following intracellular sorting.
Authors: Authors: Hrvatin S, Deng F, O'Donnell CW, Gifford DK, Melton DA.
PLoS One
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Sox17 promotes differentiation in mouse embryonic stem cells by directly regulating extraembryonic gene expression and indirectly antagonizing self-renewal.
Authors: Authors: Niakan KK, Ji H, Maehr R, Vokes SA, Rodolfa KT, Sherwood RI, Yamaki M, Dimos JT, Chen AE, Melton DA, McMahon AP, Eggan K.
Genes Dev
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All beta cells contribute equally to islet growth and maintenance.
Authors: Authors: Brennand K, Huangfu D, Melton D.
PLoS Biol
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Global expression analysis of gene regulatory pathways during endocrine pancreatic development.
Authors: Authors: Gu G, Wells JM, Dombkowski D, Preffer F, Aronow B, Melton DA.
Development
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