Douglas Melton, PhD
Xander University Professor of Stem Cell and Regenerative Biology, Faculty of Arts & Sciences
Notch signaling promotes airway mucous metaplasia and inhibits alveolar development.
Authors: Authors: Guseh JS, Bores SA, Stanger BZ, Zhou Q, Anderson WJ, Melton DA, Rajagopal J.
Development
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Development
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Notch signaling reveals developmental plasticity of Pax4(+) pancreatic endocrine progenitors and shunts them to a duct fate.
Endothelial signaling during development.
Early mouse endoderm is patterned by soluble factors from adjacent germ layers.
Induction of axial mesoderm by zDVR-1, the zebrafish orthologue of Xenopus Vg1.
A truncated activin receptor inhibits mesoderm induction and formation of axial structures in Xenopus embryos.
Interaction between peptide growth factors and homoeobox genes in the establishment of antero-posterior polarity in frog embryos.
Identification of a LIF-Responsive, Replication-Competent Subpopulation of Human ß Cells.
Authors: Authors: Rosado-Olivieri EA, Aigha II, Kenty JH, Melton DA.
Cell Metab
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Cell Metab
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Establishment of human pluripotent stem cell-derived pancreatic ß-like cells in the mouse pancreas.
Authors: Authors: Ma H, Wert KJ, Shvartsman D, Melton DA, Jaenisch R.
Proc Natl Acad Sci U S A
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Proc Natl Acad Sci U S A
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How to make a functional ß-cell.