Douglas Melton, PhD
Xander University Professor of Stem Cell and Regenerative Biology, Faculty of Arts & Sciences
A truncated activin receptor inhibits mesoderm induction and formation of axial structures in Xenopus embryos.
Interaction between peptide growth factors and homoeobox genes in the establishment of antero-posterior polarity in frog embryos.
Circadian Entrainment Triggers Maturation of Human In Vitro Islets.
Authors: Authors: Alvarez-Dominguez JR, Donaghey J, Rasouli N, Kenty JHR, Helman A, Charlton J, Straubhaar JR, Meissner A, Melton DA.
Cell Stem Cell
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Cell Stem Cell
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Corrigendum: Generation of stem cell-derived ß-cells from patients with type 1 diabetes.
Authors: Authors: Millman JR, Xie C, Van Dervort A, Gürtler M, Pagliuca FW, Melton DA.
Nat Commun
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Nat Commun
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Betatrophin: a hormone that controls pancreatic ß cell proliferation.
A small molecule that directs differentiation of human ESCs into the pancreatic lineage.
Authors: Authors: Chen S, Borowiak M, Fox JL, Maehr R, Osafune K, Davidow L, Lam K, Peng LF, Schreiber SL, Rubin LL, Melton D.
Nat Chem Biol
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Nat Chem Biol
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The vascular basement membrane: a niche for insulin gene expression and Beta cell proliferation.
Authors: Authors: Nikolova G, Jabs N, Konstantinova I, Domogatskaya A, Tryggvason K, Sorokin L, Fässler R, Gu G, Gerber HP, Ferrara N, Melton DA, Lammert E.
Dev Cell
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Dev Cell
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Single-cell transcript analysis of pancreas development.
Endoderm development: from patterning to organogenesis.
TGF-beta signals and a pattern in Xenopus laevis endodermal development.
Authors: Authors: Henry GL, Brivanlou IH, Kessler DS, Hemmati-Brivanlou A, Melton DA.
Development
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Development
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