Douglas Melton, PhD
Xander University Professor of Stem Cell and Regenerative Biology, Faculty of Arts & Sciences
Modeling Type 1 Diabetes In Vitro Using Human Pluripotent Stem Cells.
Authors: Authors: Leite NC, Sintov E, Meissner TB, Brehm MA, Greiner DL, Harlan DM, Melton DA.
Cell Rep
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Cell Rep
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YAP inhibition enhances the differentiation of functional stem cell-derived insulin-producing ß cells.
Authors: Authors: Rosado-Olivieri EA, Anderson K, Kenty JH, Melton DA.
Nat Commun
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Nat Commun
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Testing pancreatic islet function at the single cell level by calcium influx with associated marker expression.
Reprogramming within hours following nuclear transfer into mouse but not human zygotes.
Authors: Authors: Egli D, Chen AE, Saphier G, Ichida J, Fitzgerald C, Go KJ, Acevedo N, Patel J, Baetscher M, Kearns WG, Goland R, Leibel RL, Melton DA, Eggan K.
Nat Commun
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Nat Commun
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Marked differences in differentiation propensity among human embryonic stem cell lines.
Authors: Authors: Osafune K, Caron L, Borowiak M, Martinez RJ, Fitz-Gerald CS, Sato Y, Cowan CA, Chien KR, Melton DA.
Nat Biotechnol
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Nat Biotechnol
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How important are adult stem cells for tissue maintenance?
Pancreatic lineage analysis using a retroviral vector in embryonic mice demonstrates a common progenitor for endocrine and exocrine cells.
Notochord to endoderm signaling is required for pancreas development.
Mesodermal patterning by an inducer gradient depends on secondary cell-cell communication.
In situ hyridization.
Authors: Authors: O'Keefe HP, Melton DA, Ferreiro B, Kintner C.
Methods Cell Biol
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Methods Cell Biol
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