Douglas Melton, PhD
Xander University Professor of Stem Cell and Regenerative Biology, Faculty of Arts & Sciences
Effects of eight growth factors on the differentiation of cells derived from human embryonic stem cells.
Authors: Authors: Schuldiner M, Yanuka O, Itskovitz-Eldor J, Melton DA, Benvenisty N.
Proc Natl Acad Sci U S A
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Proc Natl Acad Sci U S A
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Short-range signaling by candidate morphogens of the TGF beta family and evidence for a relay mechanism of induction.
Xwnt-11: a maternally expressed Xenopus wnt gene.
The stability, toxicity and effectiveness of unmodified and phosphorothioate antisense oligodeoxynucleotides in Xenopus oocytes and embryos.
Authors: Authors: Woolf TM, Jennings CG, Rebagliati M, Melton DA.
Nucleic Acids Res
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Nucleic Acids Res
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Xfin: an embryonic gene encoding a multifingered protein in Xenopus.
Exogenous GDF11, but not GDF8, reduces body weight and improves glucose homeostasis in mice.
Authors: Authors: Walker RG, Barrandon O, Poggioli T, Dagdeviren S, Carroll SH, Mills MJ, Mendello KR, Gomez Y, Loffredo FS, Pancoast JR, Macias-Trevino C, Marts C, LeClair KB, Noh HL, Kim T, Banks AS, Kim JK, Cohen DE, Wagers AJ, Melton DA, Lee RT.
Sci Rep
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Sci Rep
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Author Correction: Pancreas regeneration.
Differentiated human stem cells resemble fetal, not adult, ß cells.
Authors: Authors: Hrvatin S, O'Donnell CW, Deng F, Millman JR, Pagliuca FW, DiIorio P, Rezania A, Gifford DK, Melton DA.
Proc Natl Acad Sci U S A
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Proc Natl Acad Sci U S A
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How to make beta cells?
Organ size is limited by the number of embryonic progenitor cells in the pancreas but not the liver.