Isaac Chiu, PhD

Assistant Professor of Immunology, Harvard Medical School
Blocking Neuronal Signaling to Immune Cells Treats Streptococcal Invasive Infection.
Authors: Authors: Pinho-Ribeiro FA, Baddal B, Haarsma R, O'Seaghdha M, Yang NJ, Blake KJ, Portley M, Verri WA, Dale JB, Wessels MR, Chiu IM.
Cell
View full abstract on Pubmed
Correction: Transcriptional profiling at whole population and single cell levels reveals somatosensory neuron molecular diversity.
Authors: Authors: Chiu IM, Barrett LB, Williams EK, Strochlic DE, Lee S, Weyer AD, Lou S, Bryman G, Roberson DP, Ghasemlou N, Piccoli C, Ahat E, Wang V, Cobos EJ, Stucky CL, Ma Q, Liberles SD, Woolf C.
Elife
View full abstract on Pubmed
MLL 5 protein forms intranuclear foci, and overexpression inhibits cell cycle progression.
Authors: Authors: Deng LW, Chiu I, Strominger JL.
Proc Natl Acad Sci U S A
View full abstract on Pubmed
Nociceptor sensory neurons suppress neutrophil and ?d T cell responses in bacterial lung infections and lethal pneumonia.
Authors: Authors: Baral P, Umans BD, Li L, Wallrapp A, Bist M, Kirschbaum T, Wei Y, Zhou Y, Kuchroo VK, Burkett PR, Yipp BG, Liberles SD, Chiu IM.
Nat Med
View full abstract on Pubmed
Transcriptional profiling at whole population and single cell levels reveals somatosensory neuron molecular diversity.
Authors: Authors: Chiu IM, Barrett LB, Williams EK, Strochlic DE, Lee S, Weyer AD, Lou S, Bryman GS, Roberson DP, Ghasemlou N, Piccoli C, Ahat E, Wang V, Cobos EJ, Stucky CL, Ma Q, Liberles SD, Woolf CJ.
Elife
View full abstract on Pubmed
The human natural killer cell immune synapse.
Authors: Authors: Davis DM, Chiu I, Fassett M, Cohen GB, Mandelboim O, Strominger JL.
Proc Natl Acad Sci U S A
View full abstract on Pubmed
Staphylococcus aureus produces pain through pore-forming toxins and neuronal TRPV1 that is silenced by QX-314.
Authors: Authors: Blake KJ, Baral P, Voisin T, Lubkin A, Pinho-Ribeiro FA, Adams KL, Roberson DP, Ma YC, Otto M, Woolf CJ, Torres VJ, Chiu IM.
Nat Commun
View full abstract on Pubmed
Modeling pain in vitro using nociceptor neurons reprogrammed from fibroblasts.
Authors: Authors: Wainger BJ, Buttermore ED, Oliveira JT, Mellin C, Lee S, Saber WA, Wang AJ, Ichida JK, Chiu IM, Barrett L, Huebner EA, Bilgin C, Tsujimoto N, Brenneis C, Kapur K, Rubin LL, Eggan K, Woolf CJ.
Nat Neurosci
View full abstract on Pubmed
Trafficking of spontaneously endocytosed MHC proteins.
Authors: Authors: Chiu I, Davis DM, Strominger JL.
Proc Natl Acad Sci U S A
View full abstract on Pubmed
Erratum: The neuropeptide NMU amplifies ILC2-driven allergic lung inflammation.
Authors: Authors: Wallrapp A, Riesenfeld SJ, Burkett PR, Abdulnour RE, Nyman J, Dionne D, Hofree M, Cuoco MS, Rodman C, Farouq D, Haas BJ, Tickle TL, Trombetta JJ, Baral P, Klose CSN, Mahlakõiv T, Artis D, Rozenblatt-Rosen O, Chiu IM, Levy BD, Kowalczyk MS, Regev A, Kuchroo VK.
Nature
View full abstract on Pubmed