James Hogle, PhD
Edward S. Harkness Professor of Biological Chemistry and Molecular Pharmacology, Harvard Medical School
DNA-Corralled Nanodiscs for the Structural and Functional Characterization of Membrane Proteins and Viral Entry.
Authors: Authors: Zhao Z, Zhang M, Hogle JM, Shih WM, Wagner G, Nasr ML.
J Am Chem Soc
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J Am Chem Soc
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Cryo-electron microscopy reconstruction shows poliovirus 135S particles poised for membrane interaction and RNA release.
The positively charged surface of herpes simplex virus UL42 mediates DNA binding.
Authors: Authors: Komazin-Meredith G, Santos WL, Filman DJ, Hogle JM, Verdine GL, Coen DM.
J Biol Chem
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J Biol Chem
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Poliovirus cell entry: common structural themes in viral cell entry pathways.
Poliovirus mutants at histidine 195 of VP2 do not cleave VP0 into VP2 and VP4.
Authors: Authors: Hindiyeh M, Li QH, Basavappa R, Hogle JM, Chow M.
J Virol
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J Virol
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(E)-enolbutyryl-UDP-N-acetylglucosamine as a mechanistic probe of UDP-N-acetylenolpyruvylglucosamine reductase (MurB).
Crystal structure of selenosubtilisin at 2.0-A resolution.
Antigenic hybrids of poliovirus.
Picornavirus RNA is protected from cleavage by ribonuclease during virion uncoating and transfer across cellular and model membranes.
Authors: Authors: Groppelli E, Levy HC, Sun E, Strauss M, Nicol C, Gold S, Zhuang X, Tuthill TJ, Hogle JM, Rowlands DJ.
PLoS Pathog
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PLoS Pathog
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Conformational shift of a major poliovirus antigen confirmed by immuno-cryogenic electron microscopy.
Authors: Authors: Lin J, Cheng N, Hogle JM, Steven AC, Belnap DM.
J Immunol
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J Immunol
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