James Hogle, PhD

Edward S. Harkness Professor of Biological Chemistry and Molecular Pharmacology, Harvard Medical School
Structure of a herpesvirus nuclear egress complex subunit reveals an interaction groove that is essential for viral replication.
Authors: Authors: Leigh KE, Sharma M, Mansueto MS, Boeszoermenyi A, Filman DJ, Hogle JM, Wagner G, Coen DM, Arthanari H.
Proc Natl Acad Sci U S A
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Picornaviruses.
Authors: Authors: Tuthill TJ, Groppelli E, Hogle JM, Rowlands DJ.
Curr Top Microbiol Immunol
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Multiple conformations in the ligand-binding site of the yeast nuclear pore-targeting domain of Nup116p.
Authors: Authors: Robinson MA, Park S, Sun ZY, Silver PA, Wagner G, Hogle JM.
J Biol Chem
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Computational design of D-peptide inhibitors of hepatitis delta antigen dimerization.
Authors: Authors: Elkin CD, Zuccola HJ, Hogle JM, Joseph-McCarthy D.
J Comput Aided Mol Des
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Ligand-induced conformational changes in poliovirus-antiviral drug complexes.
Authors: Authors: Hiremath CN, Filman DJ, Grant RA, Hogle JM.
Acta Crystallogr D Biol Crystallogr
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Crystallization and preliminary X-ray crystallographic studies of UDP-N-acetylenolpyruvylglucosamine reductase.
Authors: Authors: Benson TE, Walsh CT, Hogle JM.
Protein Sci
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Cell-induced conformational change in poliovirus: externalization of the amino terminus of VP1 is responsible for liposome binding.
Authors: Authors: Fricks CE, Hogle JM.
J Virol
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Divalent cation sites in tomato bushy stunt virus. Difference maps at 2-9 A resolution.
Authors: Authors: Hogle J, Kirchhausen T, Harrison SC.
J Mol Biol
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Characterization of Poliovirus Neutralization Escape Mutants of Single-Domain Antibody Fragments (VHHs).
Authors: Authors: Schotte L, Thys B, Strauss M, Filman DJ, Rombaut B, Hogle JM.
Antimicrob Agents Chemother
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The crystal structure of PF-8, the DNA polymerase accessory subunit from Kaposi's sarcoma-associated herpesvirus.
Authors: Authors: Baltz JL, Filman DJ, Ciustea M, Silverman JE, Lautenschlager CL, Coen DM, Ricciardi RP, Hogle JM.
J Virol
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