James Hogle, PhD

Edward S. Harkness Professor of Biological Chemistry and Molecular Pharmacology, Harvard Medical School
Unexpected features and mechanism of heterodimer formation of a herpesvirus nuclear egress complex.
Authors: Authors: Lye MF, Sharma M, El Omari K, Filman DJ, Schuermann JP, Hogle JM, Coen DM.
EMBO J
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Catching a virus in the act of RNA release: a novel poliovirus uncoating intermediate characterized by cryo-electron microscopy.
Authors: Authors: Levy HC, Bostina M, Filman DJ, Hogle JM.
J Virol
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Binding of herpes simplex virus-1 US11 to specific RNA sequences.
Authors: Authors: Bryant KF, Cox JC, Wang H, Hogle JM, Ellington AD, Coen DM.
Nucleic Acids Res
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The structure and oligomerization of the yeast arginine methyltransferase, Hmt1.
Authors: Authors: Weiss VH, McBride AE, Soriano MA, Filman DJ, Silver PA, Hogle JM.
Nat Struct Biol
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The crystal structure of Dps, a ferritin homolog that binds and protects DNA.
Authors: Authors: Grant RA, Filman DJ, Finkel SE, Kolter R, Hogle JM.
Nat Struct Biol
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Structures of poliovirus complexes with anti-viral drugs: implications for viral stability and drug design.
Authors: Authors: Grant RA, Hiremath CN, Filman DJ, Syed R, Andries K, Hogle JM.
Curr Biol
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Use of type 1/type 2 chimeric polioviruses to study determinants of poliovirus type 1 neurovirulence in a mouse model.
Authors: Authors: Martin A, Benichou D, Couderc T, Hogle JM, Wychowski C, Van der Werf S, Girard M.
Virology
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Synthetic peptides from four separate regions of the poliovirus type 1 capsid protein VP1 induce neutralizing antibodies.
Authors: Authors: Chow M, Yabrov R, Bittle J, Hogle J, Baltimore D.
Proc Natl Acad Sci U S A
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Structure of a herpesvirus nuclear egress complex subunit reveals an interaction groove that is essential for viral replication.
Authors: Authors: Leigh KE, Sharma M, Mansueto MS, Boeszoermenyi A, Filman DJ, Hogle JM, Wagner G, Coen DM, Arthanari H.
Proc Natl Acad Sci U S A
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Picornaviruses.
Authors: Authors: Tuthill TJ, Groppelli E, Hogle JM, Rowlands DJ.
Curr Top Microbiol Immunol
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