James Hogle, PhD

Edward S. Harkness Professor of Biological Chemistry and Molecular Pharmacology, Harvard Medical School
Molecular tectonic model of virus structural transitions: the putative cell entry states of poliovirus.
Authors: Authors: Belnap DM, Filman DJ, Trus BL, Cheng N, Booy FP, Conway JF, Curry S, Hiremath CN, Tsang SK, Steven AC, Hogle JM.
J Virol
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Poliovirus: new insights from an old paradigm.
Authors: Authors: Wien MW, Chow M, Hogle JM.
Structure
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Characterization of poliovirus conformational alteration mediated by soluble cell receptors.
Authors: Authors: Gómez Yafal A, Kaplan G, Racaniello VR, Hogle JM.
Virology
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Structural domains of the poliovirus polyprotein are major determinants for proteolytic cleavage at Gln-Gly pairs.
Authors: Authors: Ypma-Wong MF, Filman DJ, Hogle JM, Semler BL.
J Biol Chem
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An interaction between glutathione and the capsid is required for the morphogenesis of C-cluster enteroviruses.
Authors: Authors: Ma HC, Liu Y, Wang C, Strauss M, Rehage N, Chen YH, Altan-Bonnet N, Hogle J, Wimmer E, Mueller S, Paul AV, Jiang P.
PLoS Pathog
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The human cytomegalovirus UL44 C clamp wraps around DNA.
Authors: Authors: Komazin-Meredith G, Petrella RJ, Santos WL, Filman DJ, Hogle JM, Verdine GL, Karplus M, Coen DM.
Structure
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The cytomegalovirus DNA polymerase subunit UL44 forms a C clamp-shaped dimer.
Authors: Authors: Appleton BA, Loregian A, Filman DJ, Coen DM, Hogle JM.
Mol Cell
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The crystal structure of an unusual processivity factor, herpes simplex virus UL42, bound to the C terminus of its cognate polymerase.
Authors: Authors: Zuccola HJ, Filman DJ, Coen DM, Hogle JM.
Mol Cell
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A pseudo-cell based approach to efficient crystallographic refinement of viruses.
Authors: Authors: Jacobson DH, Hogle JM, Filman DJ.
Acta Crystallogr D Biol Crystallogr
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A mutation in VP4 defines a new step in the late stages of cell entry by poliovirus.
Authors: Authors: Moscufo N, Yafal AG, Rogove A, Hogle J, Chow M.
J Virol
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