James Hogle, PhD

Edward S. Harkness Professor of Biological Chemistry and Molecular Pharmacology, Harvard Medical School
Cryo-electron microscopy reconstruction shows poliovirus 135S particles poised for membrane interaction and RNA release.
Authors: Authors: Butan C, Filman DJ, Hogle JM.
J Virol
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The positively charged surface of herpes simplex virus UL42 mediates DNA binding.
Authors: Authors: Komazin-Meredith G, Santos WL, Filman DJ, Hogle JM, Verdine GL, Coen DM.
J Biol Chem
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Poliovirus cell entry: common structural themes in viral cell entry pathways.
Authors: Authors: Hogle JM.
Annu Rev Microbiol
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Poliovirus mutants at histidine 195 of VP2 do not cleave VP0 into VP2 and VP4.
Authors: Authors: Hindiyeh M, Li QH, Basavappa R, Hogle JM, Chow M.
J Virol
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(E)-enolbutyryl-UDP-N-acetylglucosamine as a mechanistic probe of UDP-N-acetylenolpyruvylglucosamine reductase (MurB).
Authors: Authors: Lees WJ, Benson TE, Hogle JM, Walsh CT.
Biochemistry
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Crystal structure of selenosubtilisin at 2.0-A resolution.
Authors: Authors: Syed R, Wu ZP, Hogle JM, Hilvert D.
Biochemistry
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Antigenic hybrids of poliovirus.
Authors: Authors: Hogle JM.
Nature
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Picornavirus RNA is protected from cleavage by ribonuclease during virion uncoating and transfer across cellular and model membranes.
Authors: Authors: Groppelli E, Levy HC, Sun E, Strauss M, Nicol C, Gold S, Zhuang X, Tuthill TJ, Hogle JM, Rowlands DJ.
PLoS Pathog
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Conformational shift of a major poliovirus antigen confirmed by immuno-cryogenic electron microscopy.
Authors: Authors: Lin J, Cheng N, Hogle JM, Steven AC, Belnap DM.
J Immunol
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Single particle cryoelectron tomography characterization of the structure and structural variability of poliovirus-receptor-membrane complex at 30 A resolution.
Authors: Authors: Bostina M, Bubeck D, Schwartz C, Nicastro D, Filman DJ, Hogle JM.
J Struct Biol
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