James Hogle, PhD

Edward S. Harkness Professor of Biological Chemistry and Molecular Pharmacology, Harvard Medical School
Crystal structure of a 14 bp RNA duplex with non-symmetrical tandem GxU wobble base pairs.
Authors: Authors: Trikha J, Filman DJ, Hogle JM.
Nucleic Acids Res
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An enzyme-substrate complex involved in bacterial cell wall biosynthesis.
Authors: Authors: Benson TE, Filman DJ, Walsh CT, Hogle JM.
Nat Struct Biol
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Poliovirus chimeras expressing sequences from the principal neutralization domain of human immunodeficiency virus type 1.
Authors: Authors: Dedieu JF, Ronco J, van der Werf S, Hogle JM, Henin Y, Girard M.
J Virol
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The structure of poliovirus.
Authors: Authors: Hogle JM, Chow M, Filman DJ.
Sci Am
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Cryo-electron Microscopy Structures of Expanded Poliovirus with VHHs Sample the Conformational Repertoire of the Expanded State.
Authors: Authors: Strauss M, Schotte L, Karunatilaka KS, Filman DJ, Hogle JM.
J Virol
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RNA transfer from poliovirus 135S particles across membranes is mediated by long umbilical connectors.
Authors: Authors: Strauss M, Levy HC, Bostina M, Filman DJ, Hogle JM.
J Virol
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Imaging poliovirus entry in live cells.
Authors: Authors: Brandenburg B, Lee LY, Lakadamyali M, Rust MJ, Zhuang X, Hogle JM.
PLoS Biol
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Molecular genetic analysis of revertants from a poliovirus mutant that is specifically adapted to the mouse spinal cord.
Authors: Authors: Jia Q, Hogle JM, Hashikawa T, Nomoto A.
J Virol
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The enzymological basis for resistance of herpesvirus DNA polymerase mutants to acyclovir: relationship to the structure of alpha-like DNA polymerases.
Authors: Authors: Huang L, Ishii KK, Zuccola H, Gehring AM, Hwang CB, Hogle J, Coen DM.
Proc Natl Acad Sci U S A
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Binding of the antiviral drug WIN51711 to the sabin strain of type 3 poliovirus: structural comparison with drug binding in rhinovirus 14.
Authors: Authors: Hiremath CN, Grant RA, Filman DJ, Hogle JM.
Acta Crystallogr D Biol Crystallogr
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