James Hogle, PhD

Edward S. Harkness Professor of Biological Chemistry and Molecular Pharmacology, Harvard Medical School
Mechanism of action and capsid-stabilizing properties of VHHs with an in vitro antipolioviral activity.
Authors: Authors: Schotte L, Strauss M, Thys B, Halewyck H, Filman DJ, Bostina M, Hogle JM, Rombaut B.
J Virol
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Post-imaging fiducial markers aid in the orientation determination of complexes with mixed or unknown symmetry.
Authors: Authors: Bubeck D, Filman DJ, Kuzmin M, Fuller SD, Hogle JM.
J Struct Biol
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Residues of human cytomegalovirus DNA polymerase catalytic subunit UL54 that are necessary and sufficient for interaction with the accessory protein UL44.
Authors: Authors: Loregian A, Appleton BA, Hogle JM, Coen DM.
J Virol
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Three-dimensional structure of poliovirus receptor bound to poliovirus.
Authors: Authors: Belnap DM, McDermott BM, Filman DJ, Cheng N, Trus BL, Zuccola HJ, Racaniello VR, Hogle JM, Steven AC.
Proc Natl Acad Sci U S A
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A genetic algorithm for the ab initio phasing of icosahedral viruses.
Authors: Authors: Miller ST, Hogle JM, Filman DJ.
Acta Crystallogr D Biol Crystallogr
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Molecular characterization of mouse-virulent poliovirus type 1 Mahoney mutants: involvement of residues of polypeptides VP1 and VP2 located on the inner surface of the capsid protein shell.
Authors: Authors: Couderc T, Hogle J, Le Blay H, Horaud F, Blondel B.
J Virol
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Three-dimensional structure of poliovirus serotype 1 neutralizing determinants.
Authors: Authors: Page GS, Mosser AG, Hogle JM, Filman DJ, Rueckert RR, Chow M.
J Virol
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DNA-Corralled Nanodiscs for the Structural and Functional Characterization of Membrane Proteins and Viral Entry.
Authors: Authors: Zhao Z, Zhang M, Hogle JM, Shih WM, Wagner G, Nasr ML.
J Am Chem Soc
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Cryo-electron microscopy reconstruction shows poliovirus 135S particles poised for membrane interaction and RNA release.
Authors: Authors: Butan C, Filman DJ, Hogle JM.
J Virol
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The positively charged surface of herpes simplex virus UL42 mediates DNA binding.
Authors: Authors: Komazin-Meredith G, Santos WL, Filman DJ, Hogle JM, Verdine GL, Coen DM.
J Biol Chem
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