James Hogle, PhD

Edward S. Harkness Professor of Biological Chemistry and Molecular Pharmacology, Harvard Medical School
Role and mechanism of the maturation cleavage of VP0 in poliovirus assembly: structure of the empty capsid assembly intermediate at 2.9 A resolution.
Authors: Authors: Basavappa R, Syed R, Flore O, Icenogle JP, Filman DJ, Hogle JM.
Protein Sci
View full abstract on Pubmed
Neutralizing antibody to Mengo virus, induced by synthetic peptides.
Authors: Authors: Muir S, Weintraub JP, Hogle J, Bittle JL.
J Gen Virol
View full abstract on Pubmed
Trypsin sensitivity of the Sabin strain of type 1 poliovirus: cleavage sites in virions and related particles.
Authors: Authors: Fricks CE, Icenogle JP, Hogle JM.
J Virol
View full abstract on Pubmed
Unexpected features and mechanism of heterodimer formation of a herpesvirus nuclear egress complex.
Authors: Authors: Lye MF, Sharma M, El Omari K, Filman DJ, Schuermann JP, Hogle JM, Coen DM.
EMBO J
View full abstract on Pubmed
Catching a virus in the act of RNA release: a novel poliovirus uncoating intermediate characterized by cryo-electron microscopy.
Authors: Authors: Levy HC, Bostina M, Filman DJ, Hogle JM.
J Virol
View full abstract on Pubmed
Binding of herpes simplex virus-1 US11 to specific RNA sequences.
Authors: Authors: Bryant KF, Cox JC, Wang H, Hogle JM, Ellington AD, Coen DM.
Nucleic Acids Res
View full abstract on Pubmed
The structure and oligomerization of the yeast arginine methyltransferase, Hmt1.
Authors: Authors: Weiss VH, McBride AE, Soriano MA, Filman DJ, Silver PA, Hogle JM.
Nat Struct Biol
View full abstract on Pubmed
The crystal structure of Dps, a ferritin homolog that binds and protects DNA.
Authors: Authors: Grant RA, Filman DJ, Finkel SE, Kolter R, Hogle JM.
Nat Struct Biol
View full abstract on Pubmed
Structures of poliovirus complexes with anti-viral drugs: implications for viral stability and drug design.
Authors: Authors: Grant RA, Hiremath CN, Filman DJ, Syed R, Andries K, Hogle JM.
Curr Biol
View full abstract on Pubmed
Use of type 1/type 2 chimeric polioviruses to study determinants of poliovirus type 1 neurovirulence in a mouse model.
Authors: Authors: Martin A, Benichou D, Couderc T, Hogle JM, Wychowski C, Van der Werf S, Girard M.
Virology
View full abstract on Pubmed