James Hogle, PhD

Edward S. Harkness Professor of Biological Chemistry and Molecular Pharmacology, Harvard Medical School
A 3D framework for understanding enterovirus 71.
Authors: Authors: Hogle JM.
Nat Struct Mol Biol
View full abstract on Pubmed
Identification of a glycosaminoglycan binding region of the alpha C protein that mediates entry of group B Streptococci into host cells.
Authors: Authors: Baron MJ, Filman DJ, Prophete GA, Hogle JM, Madoff LC.
J Biol Chem
View full abstract on Pubmed
Functional group placement in protein binding sites: a comparison of GRID and MCSS.
Authors: Authors: Bitetti-Putzer R, Joseph-McCarthy D, Hogle JM, Karplus M.
J Comput Aided Mol Des
View full abstract on Pubmed
Structure determination of echovirus 1.
Authors: Authors: Filman DJ, Wien MW, Cunningham JA, Bergelson JM, Hogle JM.
Acta Crystallogr D Biol Crystallogr
View full abstract on Pubmed
Binding of the antiviral drug WIN51711 to the sabin strain of type 3 poliovirus: structural comparison with drug binding in rhinovirus 14.
Authors: Authors: Hiremath CN, Grant RA, Filman DJ, Hogle JM.
Acta Crystallogr D Biol Crystallogr
View full abstract on Pubmed
Three-dimensional structure of Theiler virus.
Authors: Authors: Grant RA, Filman DJ, Fujinami RS, Icenogle JP, Hogle JM.
Proc Natl Acad Sci U S A
View full abstract on Pubmed
Structure and assembly of turnip crinkle virus. I. X-ray crystallographic structure analysis at 3.2 A resolution.
Authors: Authors: Hogle JM, Maeda A, Harrison SC.
J Mol Biol
View full abstract on Pubmed
A Small Covalent Allosteric Inhibitor of Human Cytomegalovirus DNA Polymerase Subunit Interactions.
Authors: Authors: Chen H, Coseno M, Ficarro SB, Mansueto MS, Komazin-Meredith G, Boissel S, Filman DJ, Marto JA, Hogle JM, Coen DM.
ACS Infect Dis
View full abstract on Pubmed
Structure of the Fab-labeled "breathing" state of native poliovirus.
Authors: Authors: Lin J, Lee LY, Roivainen M, Filman DJ, Hogle JM, Belnap DM.
J Virol
View full abstract on Pubmed
Crystal structure of poliovirus 3CD protein: virally encoded protease and precursor to the RNA-dependent RNA polymerase.
Authors: Authors: Marcotte LL, Wass AB, Gohara DW, Pathak HB, Arnold JJ, Filman DJ, Cameron CE, Hogle JM.
J Virol
View full abstract on Pubmed