James Hogle, PhD
Edward S. Harkness Professor of Biological Chemistry and Molecular Pharmacology, Harvard Medical School
Cell-induced conformational change in poliovirus: externalization of the amino terminus of VP1 is responsible for liposome binding.
Divalent cation sites in tomato bushy stunt virus. Difference maps at 2-9 A resolution.
Characterization of Poliovirus Neutralization Escape Mutants of Single-Domain Antibody Fragments (VHHs).
Authors: Authors: Schotte L, Thys B, Strauss M, Filman DJ, Rombaut B, Hogle JM.
Antimicrob Agents Chemother
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Antimicrob Agents Chemother
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The crystal structure of PF-8, the DNA polymerase accessory subunit from Kaposi's sarcoma-associated herpesvirus.
Authors: Authors: Baltz JL, Filman DJ, Ciustea M, Silverman JE, Lautenschlager CL, Coen DM, Ricciardi RP, Hogle JM.
J Virol
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J Virol
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Cryo-electron microscopy reconstruction of a poliovirus-receptor-membrane complex.
Is the 135S poliovirus particle an intermediate during cell entry?
Use of the multiple copy simultaneous search (MCSS) method to design a new class of picornavirus capsid binding drugs.
Poliovirus neutralization by antibodies to internal epitopes of VP4 and VP1 results from reversible exposure of these sequences at physiological temperature.
Alteration of amino acid 101 within capsid protein VP-1 changes the pathogenicity of Theiler's murine encephalomyelitis virus.
Generation of protein-reactive antibodies by short peptides is an event of high frequency: implications for the structural basis of immune recognition.
Authors: Authors: Niman HL, Houghten RA, Walker LE, Reisfeld RA, Wilson IA, Hogle JM, Lerner RA.
Proc Natl Acad Sci U S A
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Proc Natl Acad Sci U S A
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