Johan Paulsson, PhD
Professor of Systems Biology, Harvard Medical School
Mechanical slowing-down of cytoplasmic diffusion allows in vivo counting of proteins in individual cells.
Authors: Authors: Okumus B, Landgraf D, Lai GC, Bakshi S, Arias-Castro JC, Yildiz S, Huh D, Fernandez-Lopez R, Peterson CN, Toprak E, El Karoui M, Paulsson J.
Nat Commun
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Nat Commun
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Non-genetic heterogeneity from stochastic partitioning at cell division.
Multileveled selection on plasmid replication.
Exploiting Natural Fluctuations to Identify Kinetic Mechanisms in Sparsely Characterized Systems.
Fundamental limits on the suppression of molecular fluctuations.
Origin pairing ('handcuffing') as a mode of negative control of P1 plasmid copy number.
Stochastic activation of a DNA damage response causes cell-to-cell mutation rate variation.
Authors: Authors: Uphoff S, Lord ND, Okumus B, Potvin-Trottier L, Sherratt DJ, Paulsson J.
Science
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Science
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Site-specific modification of Alzheimer's peptides by cholesterol oxidation products enhances aggregation energetics and neurotoxicity.
Authors: Authors: Usui K, Hulleman JD, Paulsson JF, Siegel SJ, Powers ET, Kelly JW.
Proc Natl Acad Sci U S A
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Proc Natl Acad Sci U S A
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Noise in a minimal regulatory network: plasmid copy number control.
Constraints on Fluctuations in Sparsely Characterized Biological Systems.
Authors: Authors: Hilfinger A, Norman TM, Vinnicombe G, Paulsson J.
Phys Rev Lett
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Phys Rev Lett
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