John Mekalanos, PhD

Adele Lehman Professor of Microbiology and Molecular Genetics, Harvard Medical School
Long-term Persistence of an Extensively Drug-Resistant Subclade of Globally Distributed Pseudomonas aeruginosa Clonal Complex 446 in an Academic Medical Center.
Authors: Authors: Pincus NB, Bachta KER, Ozer EA, Allen JP, Pura ON, Qi C, Rhodes NJ, Marty FM, Pandit A, Mekalanos JJ, Oliver A, Hauser AR.
Clin Infect Dis
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The Drosophila Immune Deficiency Pathway Modulates Enteroendocrine Function and Host Metabolism.
Authors: Authors: Kamareddine L, Robins WP, Berkey CD, Mekalanos JJ, Watnick PI.
Cell Metab
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The acetate switch of an intestinal pathogen disrupts host insulin signaling and lipid metabolism.
Authors: Authors: Hang S, Purdy AE, Robins WP, Wang Z, Mandal M, Chang S, Mekalanos JJ, Watnick PI.

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Tit-for-tat: type VI secretion system counterattack during bacterial cell-cell interactions.
Authors: Authors: Basler M, Ho BT, Mekalanos JJ.
Cell
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Mapping the regulon of Vibrio cholerae ferric uptake regulator expands its known network of gene regulation.
Authors: Authors: Davies BW, Bogard RW, Mekalanos JJ.
Proc Natl Acad Sci U S A
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Type VI secretion apparatus and phage tail-associated protein complexes share a common evolutionary origin.
Authors: Authors: Leiman PG, Basler M, Ramagopal UA, Bonanno JB, Sauder JM, Pukatzki S, Burley SK, Almo SC, Mekalanos JJ.
Proc Natl Acad Sci U S A
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Virstatin inhibits dimerization of the transcriptional activator ToxT.
Authors: Authors: Shakhnovich EA, Hung DT, Pierson E, Lee K, Mekalanos JJ.
Proc Natl Acad Sci U S A
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Genomic sequence and receptor for the Vibrio cholerae phage KSF-1phi: evolutionary divergence among filamentous vibriophages mediating lateral gene transfer.
Authors: Authors: Faruque SM, Bin Naser I, Fujihara K, Diraphat P, Chowdhury N, Kamruzzaman M, Qadri F, Yamasaki S, Ghosh AN, Mekalanos JJ.
J Bacteriol
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Examination of diverse toxin-coregulated pilus-positive Vibrio cholerae strains fails to demonstrate evidence for Vibrio pathogenicity island phage.
Authors: Authors: Faruque SM, Zhu J, Kamruzzaman M, Mekalanos JJ.
Infect Immun
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Vibrio cholerae tolC is required for bile resistance and colonization.
Authors: Authors: Bina JE, Mekalanos JJ.
Infect Immun
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