John Mekalanos, PhD

Adele Lehman Professor of Microbiology and Molecular Genetics, Harvard Medical School
Genetic characterization of a new type IV-A pilus gene cluster found in both classical and El Tor biotypes of Vibrio cholerae.
Authors: Authors: Fullner KJ, Mekalanos JJ.
Infect Immun
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Nucleotide sequence and spatiotemporal expression of the Vibrio cholerae vieSAB genes during infection.
Authors: Authors: Lee SH, Angelichio MJ, Mekalanos JJ, Camilli A.
J Bacteriol
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Characterization of Vibrio cholerae bacteriophage K139 and use of a novel mini-transposon to identify a phage-encoded virulence factor.
Authors: Authors: Reidl J, Mekalanos JJ.
Mol Microbiol
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Use of genetic recombination as a reporter of gene expression.
Authors: Authors: Camilli A, Beattie DT, Mekalanos JJ.
Proc Natl Acad Sci U S A
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Reversion of recombinant toxoids: mutations in diphtheria toxin that partially compensate for active-site deletions.
Authors: Authors: Killeen KP, Escuyer V, Mekalanos JJ, Collier RJ.
Proc Natl Acad Sci U S A
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Characterization of defensin resistance phenotypes associated with mutations in the phoP virulence regulon of Salmonella typhimurium.
Authors: Authors: Miller SI, Pulkkinen WS, Selsted ME, Mekalanos JJ.
Infect Immun
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Toxin, toxin-coregulated pili, and the toxR regulon are essential for Vibrio cholerae pathogenesis in humans.
Authors: Authors: Herrington DA, Hall RH, Losonsky G, Mekalanos JJ, Taylor RK, Levine MM.
J Exp Med
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Effect of a recA mutation on cholera toxin gene amplification and deletion events.
Authors: Authors: Goldberg I, Mekalanos JJ.
J Bacteriol
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Genetic mapping of toxin regulatory mutations in Vibrio cholerae.
Authors: Authors: Mekalanos JJ, Sublett RD, Romig WR.
J Bacteriol
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CBASS Immunity Uses CARF-Related Effectors to Sense 3'-5'- and 2'-5'-Linked Cyclic Oligonucleotide Signals and Protect Bacteria from Phage Infection.
Authors: Authors: Lowey B, Whiteley AT, Keszei AFA, Morehouse BR, Mathews IT, Antine SP, Cabrera VJ, Kashin D, Niemann P, Jain M, Schwede F, Mekalanos JJ, Shao S, Lee ASY, Kranzusch PJ.
Cell
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