John Mekalanos, PhD

Adele Lehman Professor of Microbiology and Molecular Genetics, Harvard Medical School
Fitness cost of antibiotic susceptibility during bacterial infection.
Authors: Authors: Roux D, Danilchanka O, Guillard T, Cattoir V, Aschard H, Fu Y, Angoulvant F, Messika J, Ricard JD, Mekalanos JJ, Lory S, Pier GB, Skurnik D.
Sci Transl Med
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Vaccine economics: what price human life?
Authors: Authors: Mekalanos JJ.
Sci Transl Med
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Sigma E regulators control hemolytic activity and virulence in a shrimp pathogenic Vibrio harveyi.
Authors: Authors: Rattanama P, Thompson JR, Kongkerd N, Srinitiwarawong K, Vuddhakul V, Mekalanos JJ.
PLoS One
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Quorum-regulated biofilms enhance the development of conditionally viable, environmental Vibrio cholerae.
Authors: Authors: Kamruzzaman M, Udden SM, Cameron DE, Calderwood SB, Nair GB, Mekalanos JJ, Faruque SM.
Proc Natl Acad Sci U S A
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A type III secretion system in Vibrio cholerae translocates a formin/spire hybrid-like actin nucleator to promote intestinal colonization.
Authors: Authors: Tam VC, Serruto D, Dziejman M, Brieher W, Mekalanos JJ.

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Small-molecule inhibitor of Vibrio cholerae virulence and intestinal colonization.
Authors: Authors: Hung DT, Shakhnovich EA, Pierson E, Mekalanos JJ.
Science
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Genetic diversity and virulence potential of environmental Vibrio cholerae population in a cholera-endemic area.
Authors: Authors: Faruque SM, Chowdhury N, Kamruzzaman M, Dziejman M, Rahman MH, Sack DA, Nair GB, Mekalanos JJ.
Proc Natl Acad Sci U S A
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RS1 element of Vibrio cholerae can propagate horizontally as a filamentous phage exploiting the morphogenesis genes of CTXphi.
Authors: Authors: Faruque SM, Kamruzzaman M, Nandi RK, Ghosh AN, Nair GB, Mekalanos JJ, Sack DA.
Infect Immun
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Use of lambda phage S and R gene products in an inducible lysis system for Vibrio cholerae- and Salmonella enterica serovar typhimurium-based DNA vaccine delivery systems.
Authors: Authors: Jain V, Mekalanos JJ.
Infect Immun
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Induction of the lysogenic phage encoding cholera toxin in naturally occurring strains of toxigenic Vibrio cholerae O1 and O139.
Authors: Authors: Faruque SM, Alim AR, Albert MJ, Islam KM, Mekalanos JJ.
Infect Immun
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