John Mekalanos, PhD
Adele Lehman Professor of Microbiology and Molecular Genetics, Harvard Medical School
Transposon-based approaches to identify essential bacterial genes.
Bacterial mucosal vaccines: Vibrio cholerae as a live attenuated vaccine/vector paradigm.
Authors: Authors: Killeen K, Spriggs D, Mekalanos J.
Curr Top Microbiol Immunol
View full abstract on Pubmed
Curr Top Microbiol Immunol
View full abstract on Pubmed
Differential regulation of multiple flagellins in Vibrio cholerae.
Safety, immunogenicity, and efficacy of live attenuated Vibrio cholerae O139 vaccine prototype.
Authors: Authors: Coster TS, Killeen KP, Waldor MK, Beattie DT, Spriggs DR, Kenner JR, Trofa A, Sadoff JC, Mekalanos JJ, Taylor DN.
Lancet
View full abstract on Pubmed
Lancet
View full abstract on Pubmed
ToxR regulates virulence gene expression in non-O1 strains of Vibrio cholerae that cause epidemic cholera.
Environmental signals controlling expression of virulence determinants in bacteria.
Antibodies directed against the toxin-coregulated pilus isolated from Vibrio cholerae provide protection in the infant mouse experimental cholera model.
Safe, live Vibrio cholerae vaccines?
Authors: Authors: Taylor R, Shaw C, Peterson K, Spears P, Mekalanos J.
Vaccine
View full abstract on Pubmed
Vaccine
View full abstract on Pubmed
Genetic analysis of the cholera toxin-positive regulatory gene toxR.
Affinity filters, a new approach to the isolation of tox mutants of Vibrio cholerae.
Authors: Authors: Mekalanos JJ, Collier RJ, Romig WR.
Proc Natl Acad Sci U S A
View full abstract on Pubmed
Proc Natl Acad Sci U S A
View full abstract on Pubmed