John Mekalanos, PhD
Adele Lehman Professor of Microbiology and Molecular Genetics, Harvard Medical School
Alterations in Vibrio cholerae motility phenotypes correlate with changes in virulence factor expression.
Analysis of membrane protein interaction: ToxR can dimerize the amino terminus of phage lambda repressor.
Bacterial response to host signals: analysis and applications.
Periplasmic interaction between two membrane regulatory proteins, ToxR and ToxS, results in signal transduction and transcriptional activation.
Strategies for the development of vaccines for typhoid fever, shigellosis, and cholera.
Nucleotide sequence of the Shiga-like toxin genes of Escherichia coli.
Authors: Authors: Calderwood SB, Auclair F, Donohue-Rolfe A, Keusch GT, Mekalanos JJ.
Proc Natl Acad Sci U S A
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Proc Natl Acad Sci U S A
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Duplication and amplification of toxin genes in Vibrio cholerae.
Endogenous membrane stress induces T6SS activity in Pseudomonas aeruginosa.
Authors: Authors: Stolle AS, Meader BT, Toska J, Mekalanos JJ.
Proc Natl Acad Sci U S A
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Proc Natl Acad Sci U S A
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Farewell Stan Stanley Falkow: 1934-2018.
Authors: Authors: Cabello FC, Cohen SN, Curtiss R, Dougan G, van Embden J, Finlay BB, Heffron F, Helinski D, Hull R, Hull S, Isberg R, Kopecko DJ, Levy S, Mekalanos J, Ortiz JM, Rappuoli R, Roberts MC, So M, Timmis KN.
Environ Microbiol
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Environ Microbiol
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Secretome analysis of Vibrio cholerae type VI secretion system reveals a new effector-immunity pair.