John Mekalanos, PhD

Adele Lehman Professor of Microbiology and Molecular Genetics, Harvard Medical School
The cyclic AMP (cAMP)-cAMP receptor protein signaling system mediates resistance of Vibrio cholerae O1 strains to multiple environmental bacteriophages.
Authors: Authors: Zahid MS, Waise TM, Kamruzzaman M, Ghosh AN, Nair GB, Mekalanos JJ, Faruque SM.
Appl Environ Microbiol
View full abstract on Pubmed
Molecular mechanisms of virstatin resistance by non-O1/non-O139 strains of Vibrio cholerae.
Authors: Authors: Shakhnovich EA, Sturtevant D, Mekalanos JJ.
Mol Microbiol
View full abstract on Pubmed
Metabolic regulation of type III secretion gene expression in Pseudomonas aeruginosa.
Authors: Authors: Rietsch A, Mekalanos JJ.
Mol Microbiol
View full abstract on Pubmed
Effect of metabolic imbalance on expression of type III secretion genes in Pseudomonas aeruginosa.
Authors: Authors: Rietsch A, Wolfgang MC, Mekalanos JJ.
Infect Immun
View full abstract on Pubmed
Quorum-sensing regulators control virulence gene expression in Vibrio cholerae.
Authors: Authors: Zhu J, Miller MB, Vance RE, Dziejman M, Bassler BL, Mekalanos JJ.
Proc Natl Acad Sci U S A
View full abstract on Pubmed
Pathogens and hosts: the dance is the same, the couples are different.
Authors: Authors: Keen N, Staskawicz B, Mekalanos J, Ausubel F, Cook RJ.
Proc Natl Acad Sci U S A
View full abstract on Pubmed
Morphological and physical characterization of the capsular layer of Vibrio cholerae O139.
Authors: Authors: Meno Y, Waldor MK, Mekalanos JJ, Amako K.
Arch Microbiol
View full abstract on Pubmed
Molecular characterization of the oafA locus responsible for acetylation of Salmonella typhimurium O-antigen: oafA is a member of a family of integral membrane trans-acylases.
Authors: Authors: Slauch JM, Lee AA, Mahan MJ, Mekalanos JJ.
J Bacteriol
View full abstract on Pubmed
Monoclonal immunoglobulin A prevents adherence and invasion of polarized epithelial cell monolayers by Salmonella typhimurium.
Authors: Authors: Michetti P, Porta N, Mahan MJ, Slauch JM, Mekalanos JJ, Blum AL, Kraehenbuhl JP, Neutra MR.
Gastroenterology
View full abstract on Pubmed
Vibrio parahaemolyticus has a homolog of the Vibrio cholerae toxRS operon that mediates environmentally induced regulation of the thermostable direct hemolysin gene.
Authors: Authors: Lin Z, Kumagai K, Baba K, Mekalanos JJ, Nishibuchi M.
J Bacteriol
View full abstract on Pubmed