John Mekalanos, PhD
Adele Lehman Professor of Microbiology and Molecular Genetics, Harvard Medical School
Live bacterial vaccines: environmental aspects.
Repressor binding to a regulatory site in the DNA coding sequence is sufficient to confer transcriptional regulation of the vir-repressed genes (vrg genes) in Bordetella pertussis.
Identification and use of protective monoclonal IgA antibodies against viral and bacterial pathogens.
Authors: Authors: Neutra M, Weltzin R, Winner L, Mack J, Michetti P, Morrison L, Fields BN, Mekalanos JJ, Kraehenbuhl JP.
Adv Exp Med Biol
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Adv Exp Med Biol
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Genetic regulation of bacterial virulence.
Use of phoA gene fusions to identify a pilus colonization factor coordinately regulated with cholera toxin.
Authors: Authors: Taylor RK, Miller VL, Furlong DB, Mekalanos JJ.
Proc Natl Acad Sci U S A
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Proc Natl Acad Sci U S A
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Molecular cloning of Vibrio cholerae enterotoxin genes in Escherichia coli K-12.
Transcriptional Silencing by TsrA in the Evolution of Pathogenic Vibrio cholerae Biotypes.
Exopolysaccharide protects Vibrio cholerae from exogenous attacks by the type 6 secretion system.
Authors: Authors: Toska J, Ho BT, Mekalanos JJ.
Proc Natl Acad Sci U S A
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Proc Natl Acad Sci U S A
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Conjugate-like immunogens produced as protein capsular matrix vaccines.
Authors: Authors: Thanawastien A, Cartee RT, Griffin TJ, Killeen KP, Mekalanos JJ.
Proc Natl Acad Sci U S A
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Proc Natl Acad Sci U S A
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PAAR-repeat proteins sharpen and diversify the type VI secretion system spike.
Authors: Authors: Shneider MM, Buth SA, Ho BT, Basler M, Mekalanos JJ, Leiman PG.
Nature
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Nature
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