John Mekalanos, PhD

Adele Lehman Professor of Microbiology and Molecular Genetics, Harvard Medical School
Phase variable O antigen biosynthetic genes control expression of the major protective antigen and bacteriophage receptor in Vibrio cholerae O1.
Authors: Authors: Seed KD, Faruque SM, Mekalanos JJ, Calderwood SB, Qadri F, Camilli A.
PLoS Pathog
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Functional analysis of VopF activity required for colonization in Vibrio cholerae.
Authors: Authors: Tam VC, Suzuki M, Coughlin M, Saslowsky D, Biswas K, Lencer WI, Faruque SM, Mekalanos JJ.
mBio
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Production and sequence validation of a complete full length ORF collection for the pathogenic bacterium Vibrio cholerae.
Authors: Authors: Rolfs A, Montor WR, Yoon SS, Hu Y, Bhullar B, Kelley F, McCarron S, Jepson DA, Shen B, Taycher E, Mohr SE, Zuo D, Williamson J, Mekalanos J, Labaer J.
Proc Natl Acad Sci U S A
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Modeling the role of bacteriophage in the control of cholera outbreaks.
Authors: Authors: Jensen MA, Faruque SM, Mekalanos JJ, Levin BR.
Proc Natl Acad Sci U S A
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Bile acids induce cholera toxin expression in Vibrio cholerae in a ToxT-independent manner.
Authors: Authors: Hung DT, Mekalanos JJ.
Proc Natl Acad Sci U S A
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The contribution of accessory toxins of Vibrio cholerae O1 El Tor to the proinflammatory response in a murine pulmonary cholera model.
Authors: Authors: Fullner KJ, Boucher JC, Hanes MA, Haines GK, Meehan BM, Walchle C, Sansonetti PJ, Mekalanos JJ.
J Exp Med
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In vivo covalent cross-linking of cellular actin by the Vibrio cholerae RTX toxin.
Authors: Authors: Fullner KJ, Mekalanos JJ.
EMBO J
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ToxR co-operative interactions are not modulated by environmental conditions or periplasmic domain conformation.
Authors: Authors: Dziejman M, Kolmar H, Fritz HJ, Mekalanos JJ.
Mol Microbiol
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Regulation, replication, and integration functions of the Vibrio cholerae CTXphi are encoded by region RS2.
Authors: Authors: Waldor MK, Rubin EJ, Pearson GD, Kimsey H, Mekalanos JJ.
Mol Microbiol
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Acetylation (O-factor 5) affects the structural and immunological properties of Salmonella typhimurium lipopolysaccharide O antigen.
Authors: Authors: Slauch JM, Mahan MJ, Michetti P, Neutra MR, Mekalanos JJ.
Infect Immun
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