John Mekalanos, PhD
Adele Lehman Professor of Microbiology and Molecular Genetics, Harvard Medical School
Live attenuated vaccine vectors.
Constitutive sensory transduction mutations in the Bordetella pertussis bvgS gene.
Authors: Authors: Miller JF, Johnson SA, Black WJ, Beattie DT, Mekalanos JJ, Falkow S.
J Bacteriol
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J Bacteriol
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Salmonella vaccines with mutations in the phoP virulence regulon.
Evidence that glutamic acid 167 is an active-site residue of Shiga-like toxin I.
Authors: Authors: Hovde CJ, Calderwood SB, Mekalanos JJ, Collier RJ.
Proc Natl Acad Sci U S A
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Proc Natl Acad Sci U S A
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Identification of a pilus colonization factor that is coordinately regulated with cholera toxin.
Authors: Authors: Taylor RK, Miller VL, Furlong DB, Mekalanos JJ.
Ann Sclavo Collana Monogr
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Ann Sclavo Collana Monogr
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Enzymic activity of cholera toxin. I. New method of assay and the mechanism of ADP-ribosyl transfer.
Structure and Mechanism of a Cyclic Trinucleotide-Activated Bacterial Endonuclease Mediating Bacteriophage Immunity.
Authors: Authors: Lau RK, Ye Q, Birkholz EA, Berg KR, Patel L, Mathews IT, Watrous JD, Ego K, Whiteley AT, Lowey B, Mekalanos JJ, Kranzusch PJ, Jain M, Pogliano J, Corbett KD.
Mol Cell
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Mol Cell
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Draft Genome Sequence of Bowmanella denitrificans JL63, a Bacterium Isolated from Whiteleg Shrimp (Litopenaeus vannamei) That Can Inhibit the Growth of Vibrio parahaemolyticus.
Authors: Authors: LaPorte JP, Spinard EJ, Gomez-Chiarri M, Rowley DC, Mekalanos JJ, Nelson DR.
Genome Announc
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Genome Announc
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The highly conserved bacterial RNase YbeY is essential in Vibrio cholerae, playing a critical role in virulence, stress regulation, and RNA processing.
Authors: Authors: Vercruysse M, Köhrer C, Davies BW, Arnold MF, Mekalanos JJ, RajBhandary UL, Walker GC.
PLoS Pathog
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PLoS Pathog
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Phage-bacterial interactions in the evolution of toxigenic Vibrio cholerae.