John Mekalanos, PhD

Adele Lehman Professor of Microbiology and Molecular Genetics, Harvard Medical School
Cloning and expression of the Salmonella enterotoxin gene.
Authors: Authors: Chopra AK, Houston CW, Peterson JW, Prasad R, Mekalanos JJ.
J Bacteriol
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Genetic mapping of Vibrio cholerae enterotoxin structural genes.
Authors: Authors: Sporecke I, Castro D, Mekalanos JJ.
J Bacteriol
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Alarmone Ap4A is elevated by aminoglycoside antibiotics and enhances their bactericidal activity.
Authors: Authors: Ji X, Zou J, Peng H, Stolle AS, Xie R, Zhang H, Peng B, Mekalanos JJ, Zheng J.
Proc Natl Acad Sci U S A
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Emergence of Antimicrobial-Resistant Escherichia coli of Animal Origin Spreading in Humans.
Authors: Authors: Skurnik D, Clermont O, Guillard T, Launay A, Danilchanka O, Pons S, Diancourt L, Lebreton F, Kadlec K, Roux D, Jiang D, Dion S, Aschard H, Denamur M, Cywes-Bentley C, Schwarz S, Tenaillon O, Andremont A, Picard B, Mekalanos J, Brisse S, Denamur E.
Mol Biol Evol
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Type 6 secretion system-mediated immunity to type 4 secretion system-mediated gene transfer.
Authors: Authors: Ho BT, Basler M, Mekalanos JJ.
Science
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Type VI secretion requires a dynamic contractile phage tail-like structure.
Authors: Authors: Basler M, Pilhofer M, Henderson GP, Jensen GJ, Mekalanos JJ.
Nature
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In vivo actin cross-linking induced by Vibrio cholerae type VI secretion system is associated with intestinal inflammation.
Authors: Authors: Ma AT, Mekalanos JJ.
Proc Natl Acad Sci U S A
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Threonine phosphorylation post-translationally regulates protein secretion in Pseudomonas aeruginosa.
Authors: Authors: Mougous JD, Gifford CA, Ramsdell TL, Mekalanos JJ.
Nat Cell Biol
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Bile acids stimulate biofilm formation in Vibrio cholerae.
Authors: Authors: Hung DT, Zhu J, Sturtevant D, Mekalanos JJ.
Mol Microbiol
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The opportunistic pathogen Pseudomonas aeruginosa carries a secretable arachidonate 15-lipoxygenase.
Authors: Authors: Vance RE, Hong S, Gronert K, Serhan CN, Mekalanos JJ.
Proc Natl Acad Sci U S A
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