John Mekalanos, PhD

Adele Lehman Professor of Microbiology and Molecular Genetics, Harvard Medical School
DNA damage and reactive nitrogen species are barriers to Vibrio cholerae colonization of the infant mouse intestine.
Authors: Authors: Davies BW, Bogard RW, Dupes NM, Gerstenfeld TA, Simmons LA, Mekalanos JJ.
PLoS Pathog
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Distribution of genes for virulence and ecological fitness among diverse Vibrio cholerae population in a cholera endemic area: tracking the evolution of pathogenic strains.
Authors: Authors: Rahman MH, Biswas K, Hossain MA, Sack RB, Mekalanos JJ, Faruque SM.
DNA Cell Biol
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Characterization of the Vibrio cholerae vexAB and vexCD efflux systems.
Authors: Authors: Bina JE, Provenzano D, Wang C, Bina XR, Mekalanos JJ.
Arch Microbiol
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An open letter to Elias Zerhouni.
Authors: Authors: Altman S, Bassler BL, Beckwith J, Belfort M, Berg HC, Bloom B, Brenchley JE, Campbell A, Collier RJ, Connell N, Cozzarelli NR, Craig NL, Darst S, Ebright RH, Elledge SJ, Falkow S, Galan JE, Gottesman M, Gourse R, Grindley ND, Gross CA, Grossman A, Hochschild A, Howe M, Hurwitz J, Isberg RR, Kaplan S, Kornberg A, Kustu SG, Landick RC, Landy A, Levy SB, Losick R, Long SR, Maloy SR, Mekalanos JJ, Neidhardt FC, Pace NR, Ptashne M, Roberts JW, Roth JR, Rothman-Denes LB, Salyers A, Schaechter M, Shapiro L, Silhavy TJ, Simon MI, Walker G, Yanofsky C, Zinder N.
Science
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Determination of the transcriptome of Vibrio cholerae during intraintestinal growth and midexponential phase in vitro.
Authors: Authors: Xu Q, Dziejman M, Mekalanos JJ.
Proc Natl Acad Sci U S A
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Association of protease activity in Vibrio cholerae vaccine strains with decreases in transcellular epithelial resistance of polarized T84 intestinal epithelial cells.
Authors: Authors: Mel SF, Fullner KJ, Wimer-Mackin S, Lencer WI, Mekalanos JJ.
Infect Immun
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rfb mutations in Vibrio cholerae do not affect surface production of toxin-coregulated pili but still inhibit intestinal colonization.
Authors: Authors: Chiang SL, Mekalanos JJ.
Infect Immun
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TcpP protein is a positive regulator of virulence gene expression in Vibrio cholerae.
Authors: Authors: Häse CC, Mekalanos JJ.
Proc Natl Acad Sci U S A
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Heterologous antigen expression in Vibrio cholerae vector strains.
Authors: Authors: Butterton JR, Beattie DT, Gardel CL, Carroll PA, Hyman T, Killeen KP, Mekalanos JJ, Calderwood SB.
Infect Immun
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In vivo expression technology for selection of bacterial genes specifically induced in host tissues.
Authors: Authors: Slauch JM, Mahan MJ, Mekalanos JJ.
Methods Enzymol
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