John Mekalanos, PhD

Adele Lehman Professor of Microbiology and Molecular Genetics, Harvard Medical School
Decreased potency of the Vibrio cholerae sheathed flagellum to trigger host innate immunity.
Authors: Authors: Yoon SS, Mekalanos JJ.
Infect Immun
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Bacterial genomics and pathogen evolution.
Authors: Authors: Raskin DM, Seshadri R, Pukatzki SU, Mekalanos JJ.
Cell
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Seasonal epidemics of cholera inversely correlate with the prevalence of environmental cholera phages.
Authors: Authors: Faruque SM, Naser IB, Islam MJ, Faruque AS, Ghosh AN, Nair GB, Sack DA, Mekalanos JJ.
Proc Natl Acad Sci U S A
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YgbQ, a cell division protein in Escherichia coli and Vibrio cholerae, localizes in codependent fashion with FtsL to the division site.
Authors: Authors: Buddelmeijer N, Judson N, Boyd D, Mekalanos JJ, Beckwith J.
Proc Natl Acad Sci U S A
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DNA sequence of both chromosomes of the cholera pathogen Vibrio cholerae.
Authors: Authors: Heidelberg JF, Eisen JA, Nelson WC, Clayton RA, Gwinn ML, Dodson RJ, Haft DH, Hickey EK, Peterson JD, Umayam L, Gill SR, Nelson KE, Read TD, Tettelin H, Richardson D, Ermolaeva MD, Vamathevan J, Bass S, Qin H, Dragoi I, Sellers P, McDonald L, Utterback T, Fleishmann RD, Nierman WC, White O, Salzberg SL, Smith HO, Colwell RR, Mekalanos JJ, Venter JC, Fraser CM.
Nature
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Epidemiology, genetics, and ecology of toxigenic Vibrio cholerae.
Authors: Authors: Faruque SM, Albert MJ, Mekalanos JJ.
Microbiol Mol Biol Rev
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Modulation of horizontal gene transfer in pathogenic bacteria by in vivo signals.
Authors: Authors: Mel SF, Mekalanos JJ.
Cell
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The Vibrio cholerae O139 serogroup antigen includes an O-antigen capsule and lipopolysaccharide virulence determinants.
Authors: Authors: Waldor MK, Colwell R, Mekalanos JJ.
Proc Natl Acad Sci U S A
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Selection for bacterial genes that are specifically induced in host tissues: the hunt for virulence factors.
Authors: Authors: Mahan MJ, Slauch JM, Hanna PC, Camilli A, Tobias JW, Waldor MK, Mekalanos JJ.
Infect Agents Dis
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Regulatory cascade controls virulence in Vibrio cholerae.
Authors: Authors: DiRita VJ, Parsot C, Jander G, Mekalanos JJ.
Proc Natl Acad Sci U S A
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