John Mekalanos, PhD

Adele Lehman Professor of Microbiology and Molecular Genetics, Harvard Medical School
Role of the type III secreted exoenzymes S, T, and Y in systemic spread of Pseudomonas aeruginosa PAO1 in vivo.
Authors: Authors: Vance RE, Rietsch A, Mekalanos JJ.
Infect Immun
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CTXphi-independent production of the RS1 satellite phage by Vibrio cholerae.
Authors: Authors: Faruque SM, Kamruzzaman M, Sack DA, Mekalanos JJ, Nair GB.
Proc Natl Acad Sci U S A
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Transposon-based approaches to identify essential bacterial genes.
Authors: Authors: Judson N, Mekalanos JJ.
Trends Microbiol
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Bacterial mucosal vaccines: Vibrio cholerae as a live attenuated vaccine/vector paradigm.
Authors: Authors: Killeen K, Spriggs D, Mekalanos J.
Curr Top Microbiol Immunol
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Differential regulation of multiple flagellins in Vibrio cholerae.
Authors: Authors: Klose KE, Mekalanos JJ.
J Bacteriol
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Safety, immunogenicity, and efficacy of live attenuated Vibrio cholerae O139 vaccine prototype.
Authors: Authors: Coster TS, Killeen KP, Waldor MK, Beattie DT, Spriggs DR, Kenner JR, Trofa A, Sadoff JC, Mekalanos JJ, Taylor DN.
Lancet
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ToxR regulates virulence gene expression in non-O1 strains of Vibrio cholerae that cause epidemic cholera.
Authors: Authors: Waldor MK, Mekalanos JJ.
Infect Immun
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Environmental signals controlling expression of virulence determinants in bacteria.
Authors: Authors: Mekalanos JJ.
J Bacteriol
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Antibodies directed against the toxin-coregulated pilus isolated from Vibrio cholerae provide protection in the infant mouse experimental cholera model.
Authors: Authors: Sun DX, Mekalanos JJ, Taylor RK.
J Infect Dis
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Safe, live Vibrio cholerae vaccines?
Authors: Authors: Taylor R, Shaw C, Peterson K, Spears P, Mekalanos J.
Vaccine
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