John Mekalanos, PhD

Adele Lehman Professor of Microbiology and Molecular Genetics, Harvard Medical School
Virstatin inhibits dimerization of the transcriptional activator ToxT.
Authors: Authors: Shakhnovich EA, Hung DT, Pierson E, Lee K, Mekalanos JJ.
Proc Natl Acad Sci U S A
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Genomic sequence and receptor for the Vibrio cholerae phage KSF-1phi: evolutionary divergence among filamentous vibriophages mediating lateral gene transfer.
Authors: Authors: Faruque SM, Bin Naser I, Fujihara K, Diraphat P, Chowdhury N, Kamruzzaman M, Qadri F, Yamasaki S, Ghosh AN, Mekalanos JJ.
J Bacteriol
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Examination of diverse toxin-coregulated pilus-positive Vibrio cholerae strains fails to demonstrate evidence for Vibrio pathogenicity island phage.
Authors: Authors: Faruque SM, Zhu J, Kamruzzaman M, Mekalanos JJ.
Infect Immun
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Vibrio cholerae tolC is required for bile resistance and colonization.
Authors: Authors: Bina JE, Mekalanos JJ.
Infect Immun
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Genetic characterization of a new type IV-A pilus gene cluster found in both classical and El Tor biotypes of Vibrio cholerae.
Authors: Authors: Fullner KJ, Mekalanos JJ.
Infect Immun
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Nucleotide sequence and spatiotemporal expression of the Vibrio cholerae vieSAB genes during infection.
Authors: Authors: Lee SH, Angelichio MJ, Mekalanos JJ, Camilli A.
J Bacteriol
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Characterization of Vibrio cholerae bacteriophage K139 and use of a novel mini-transposon to identify a phage-encoded virulence factor.
Authors: Authors: Reidl J, Mekalanos JJ.
Mol Microbiol
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Use of genetic recombination as a reporter of gene expression.
Authors: Authors: Camilli A, Beattie DT, Mekalanos JJ.
Proc Natl Acad Sci U S A
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Reversion of recombinant toxoids: mutations in diphtheria toxin that partially compensate for active-site deletions.
Authors: Authors: Killeen KP, Escuyer V, Mekalanos JJ, Collier RJ.
Proc Natl Acad Sci U S A
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Characterization of defensin resistance phenotypes associated with mutations in the phoP virulence regulon of Salmonella typhimurium.
Authors: Authors: Miller SI, Pulkkinen WS, Selsted ME, Mekalanos JJ.
Infect Immun
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