John Mekalanos, PhD

Adele Lehman Professor of Microbiology and Molecular Genetics, Harvard Medical School
Antibodies directed against the toxin-coregulated pilus isolated from Vibrio cholerae provide protection in the infant mouse experimental cholera model.
Authors: Authors: Sun DX, Mekalanos JJ, Taylor RK.
J Infect Dis
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Safe, live Vibrio cholerae vaccines?
Authors: Authors: Taylor R, Shaw C, Peterson K, Spears P, Mekalanos J.
Vaccine
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Role of cholera toxin in enteric colonization by Vibrio cholerae O1 in rabbits.
Authors: Authors: Pierce NF, Kaper JB, Mekalanos JJ, Cray WC.
Infect Immun
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Purification of cholera toxin and its subunits: new methods of preparation and the use of hypertoxinogenic mutants.
Authors: Authors: Mekalanos JJ, Collier RJ, Romig WR.
Infect Immun
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A phase 1 randomized safety, reactogenicity, and immunogenicity study of Typhax: A novel protein capsular matrix vaccine candidate for the prevention of typhoid fever.
Authors: Authors: Cartee RT, Thanawastien A, Griffin Iv TJ, Mekalanos JJ, Bart S, Killeen KP.
PLoS Negl Trop Dis
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Antagonism toward the intestinal microbiota and its effect on Vibrio cholerae virulence.
Authors: Authors: Zhao W, Caro F, Robins W, Mekalanos JJ.
Science
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Proteomic analysis of Vibrio cholerae outer membrane vesicles.
Authors: Authors: Altindis E, Fu Y, Mekalanos JJ.
Proc Natl Acad Sci U S A
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MetR-regulated Vibrio cholerae metabolism is required for virulence.
Authors: Authors: Bogard RW, Davies BW, Mekalanos JJ.
mBio
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The origin of the Haitian cholera outbreak strain.
Authors: Authors: Chin CS, Sorenson J, Harris JB, Robins WP, Charles RC, Jean-Charles RR, Bullard J, Webster DR, Kasarskis A, Peluso P, Paxinos EE, Yamaichi Y, Calderwood SB, Mekalanos JJ, Schadt EE, Waldor MK.
N Engl J Med
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A defined transposon mutant library and its use in identifying motility genes in Vibrio cholerae.
Authors: Authors: Cameron DE, Urbach JM, Mekalanos JJ.
Proc Natl Acad Sci U S A
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