John Mekalanos, PhD

Adele Lehman Professor of Microbiology and Molecular Genetics, Harvard Medical School
Quorum-sensing regulators control virulence gene expression in Vibrio cholerae.
Authors: Authors: Zhu J, Miller MB, Vance RE, Dziejman M, Bassler BL, Mekalanos JJ.
Proc Natl Acad Sci U S A
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Pathogens and hosts: the dance is the same, the couples are different.
Authors: Authors: Keen N, Staskawicz B, Mekalanos J, Ausubel F, Cook RJ.
Proc Natl Acad Sci U S A
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Morphological and physical characterization of the capsular layer of Vibrio cholerae O139.
Authors: Authors: Meno Y, Waldor MK, Mekalanos JJ, Amako K.
Arch Microbiol
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Molecular characterization of the oafA locus responsible for acetylation of Salmonella typhimurium O-antigen: oafA is a member of a family of integral membrane trans-acylases.
Authors: Authors: Slauch JM, Lee AA, Mahan MJ, Mekalanos JJ.
J Bacteriol
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Monoclonal immunoglobulin A prevents adherence and invasion of polarized epithelial cell monolayers by Salmonella typhimurium.
Authors: Authors: Michetti P, Porta N, Mahan MJ, Slauch JM, Mekalanos JJ, Blum AL, Kraehenbuhl JP, Neutra MR.
Gastroenterology
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Vibrio parahaemolyticus has a homolog of the Vibrio cholerae toxRS operon that mediates environmentally induced regulation of the thermostable direct hemolysin gene.
Authors: Authors: Lin Z, Kumagai K, Baba K, Mekalanos JJ, Nishibuchi M.
J Bacteriol
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Expression of the Vibrio cholerae gene encoding aldehyde dehydrogenase is under control of ToxR, the cholera toxin transcriptional activator.
Authors: Authors: Parsot C, Mekalanos JJ.
J Bacteriol
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Broad-host-range vectors for delivery of TnphoA: use in genetic analysis of secreted virulence determinants of Vibrio cholerae.
Authors: Authors: Taylor RK, Manoil C, Mekalanos JJ.
J Bacteriol
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Nucleotide sequence of the type A staphylococcal enterotoxin gene.
Authors: Authors: Betley MJ, Mekalanos JJ.
J Bacteriol
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Synthesis of cholera toxin is positively regulated at the transcriptional level by toxR.
Authors: Authors: Miller VL, Mekalanos JJ.
Proc Natl Acad Sci U S A
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