John Mekalanos, PhD
Adele Lehman Professor of Microbiology and Molecular Genetics, Harvard Medical School
Confirmation of the Fur operator site by insertion of a synthetic oligonucleotide into an operon fusion plasmid.
Genetic analysis of the cholera toxin-positive regulatory gene toxR.
Affinity filters, a new approach to the isolation of tox mutants of Vibrio cholerae.
Authors: Authors: Mekalanos JJ, Collier RJ, Romig WR.
Proc Natl Acad Sci U S A
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Proc Natl Acad Sci U S A
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An onboard checking mechanism ensures effector delivery of the type VI secretion system in Vibrio cholerae.
Authors: Authors: Liang X, Kamal F, Pei TT, Xu P, Mekalanos JJ, Dong TG.
Proc Natl Acad Sci U S A
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Proc Natl Acad Sci U S A
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Vibrio cholerae type 6 secretion system effector trafficking in target bacterial cells.
Authors: Authors: Ho BT, Fu Y, Dong TG, Mekalanos JJ.
Proc Natl Acad Sci U S A
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Proc Natl Acad Sci U S A
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Vibrio parahaemolyticus and its specific bacteriophages as an indicator in cockles (Anadara granosa) for the risk of V. parahaemolyticus infection in Southern Thailand.
Authors: Authors: Yingkajorn M, Sermwitayawong N, Palittapongarnpimp P, Nishibuchi M, Robins WP, Mekalanos JJ, Vuddhakul V.
Microb Ecol
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Microb Ecol
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Phase variable O antigen biosynthetic genes control expression of the major protective antigen and bacteriophage receptor in Vibrio cholerae O1.
Authors: Authors: Seed KD, Faruque SM, Mekalanos JJ, Calderwood SB, Qadri F, Camilli A.
PLoS Pathog
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PLoS Pathog
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Functional analysis of VopF activity required for colonization in Vibrio cholerae.
Authors: Authors: Tam VC, Suzuki M, Coughlin M, Saslowsky D, Biswas K, Lencer WI, Faruque SM, Mekalanos JJ.
mBio
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mBio
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Production and sequence validation of a complete full length ORF collection for the pathogenic bacterium Vibrio cholerae.
Authors: Authors: Rolfs A, Montor WR, Yoon SS, Hu Y, Bhullar B, Kelley F, McCarron S, Jepson DA, Shen B, Taycher E, Mohr SE, Zuo D, Williamson J, Mekalanos J, Labaer J.
Proc Natl Acad Sci U S A
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Proc Natl Acad Sci U S A
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Modeling the role of bacteriophage in the control of cholera outbreaks.
Authors: Authors: Jensen MA, Faruque SM, Mekalanos JJ, Levin BR.
Proc Natl Acad Sci U S A
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Proc Natl Acad Sci U S A
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