John Mekalanos, PhD

Adele Lehman Professor of Microbiology and Molecular Genetics, Harvard Medical School
Bile acids induce cholera toxin expression in Vibrio cholerae in a ToxT-independent manner.
Authors: Authors: Hung DT, Mekalanos JJ.
Proc Natl Acad Sci U S A
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The contribution of accessory toxins of Vibrio cholerae O1 El Tor to the proinflammatory response in a murine pulmonary cholera model.
Authors: Authors: Fullner KJ, Boucher JC, Hanes MA, Haines GK, Meehan BM, Walchle C, Sansonetti PJ, Mekalanos JJ.
J Exp Med
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In vivo covalent cross-linking of cellular actin by the Vibrio cholerae RTX toxin.
Authors: Authors: Fullner KJ, Mekalanos JJ.
EMBO J
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ToxR co-operative interactions are not modulated by environmental conditions or periplasmic domain conformation.
Authors: Authors: Dziejman M, Kolmar H, Fritz HJ, Mekalanos JJ.
Mol Microbiol
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Regulation, replication, and integration functions of the Vibrio cholerae CTXphi are encoded by region RS2.
Authors: Authors: Waldor MK, Rubin EJ, Pearson GD, Kimsey H, Mekalanos JJ.
Mol Microbiol
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Acetylation (O-factor 5) affects the structural and immunological properties of Salmonella typhimurium lipopolysaccharide O antigen.
Authors: Authors: Slauch JM, Mahan MJ, Michetti P, Neutra MR, Mekalanos JJ.
Infect Immun
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Analysis of the roles of antilipopolysaccharide and anti-cholera toxin immunoglobulin A (IgA) antibodies in protection against Vibrio cholerae and cholera toxin by use of monoclonal IgA antibodies in vivo.
Authors: Authors: Apter FM, Michetti P, Winner LS, Mack JA, Mekalanos JJ, Neutra MR.
Infect Immun
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Characterization of vir-activated TnphoA gene fusions in Bordetella pertussis.
Authors: Authors: Finn TM, Shahin R, Mekalanos JJ.
Infect Immun
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Constitutive expression of the phoP regulon attenuates Salmonella virulence and survival within macrophages.
Authors: Authors: Miller SI, Mekalanos JJ.
J Bacteriol
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The pathogenesis and immunology of Vibrio cholerae and Bordetella pertussis.
Authors: Authors: Mekalanos JJ, Peterson KM, Finn T, Knapp S.
Antonie Van Leeuwenhoek
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