John Mekalanos, PhD

Adele Lehman Professor of Microbiology and Molecular Genetics, Harvard Medical School
Enzymic activity of cholera toxin. I. New method of assay and the mechanism of ADP-ribosyl transfer.
Authors: Authors: Mekalanos JJ, Collier RJ, Romig WR.
J Biol Chem
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Structure and Mechanism of a Cyclic Trinucleotide-Activated Bacterial Endonuclease Mediating Bacteriophage Immunity.
Authors: Authors: Lau RK, Ye Q, Birkholz EA, Berg KR, Patel L, Mathews IT, Watrous JD, Ego K, Whiteley AT, Lowey B, Mekalanos JJ, Kranzusch PJ, Jain M, Pogliano J, Corbett KD.
Mol Cell
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Draft Genome Sequence of Bowmanella denitrificans JL63, a Bacterium Isolated from Whiteleg Shrimp (Litopenaeus vannamei) That Can Inhibit the Growth of Vibrio parahaemolyticus.
Authors: Authors: LaPorte JP, Spinard EJ, Gomez-Chiarri M, Rowley DC, Mekalanos JJ, Nelson DR.
Genome Announc
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The highly conserved bacterial RNase YbeY is essential in Vibrio cholerae, playing a critical role in virulence, stress regulation, and RNA processing.
Authors: Authors: Vercruysse M, Köhrer C, Davies BW, Arnold MF, Mekalanos JJ, RajBhandary UL, Walker GC.
PLoS Pathog
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Phage-bacterial interactions in the evolution of toxigenic Vibrio cholerae.
Authors: Authors: Faruque SM, Mekalanos JJ.
Virulence
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DNA damage and reactive nitrogen species are barriers to Vibrio cholerae colonization of the infant mouse intestine.
Authors: Authors: Davies BW, Bogard RW, Dupes NM, Gerstenfeld TA, Simmons LA, Mekalanos JJ.
PLoS Pathog
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Distribution of genes for virulence and ecological fitness among diverse Vibrio cholerae population in a cholera endemic area: tracking the evolution of pathogenic strains.
Authors: Authors: Rahman MH, Biswas K, Hossain MA, Sack RB, Mekalanos JJ, Faruque SM.
DNA Cell Biol
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Characterization of the Vibrio cholerae vexAB and vexCD efflux systems.
Authors: Authors: Bina JE, Provenzano D, Wang C, Bina XR, Mekalanos JJ.
Arch Microbiol
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An open letter to Elias Zerhouni.
Authors: Authors: Altman S, Bassler BL, Beckwith J, Belfort M, Berg HC, Bloom B, Brenchley JE, Campbell A, Collier RJ, Connell N, Cozzarelli NR, Craig NL, Darst S, Ebright RH, Elledge SJ, Falkow S, Galan JE, Gottesman M, Gourse R, Grindley ND, Gross CA, Grossman A, Hochschild A, Howe M, Hurwitz J, Isberg RR, Kaplan S, Kornberg A, Kustu SG, Landick RC, Landy A, Levy SB, Losick R, Long SR, Maloy SR, Mekalanos JJ, Neidhardt FC, Pace NR, Ptashne M, Roberts JW, Roth JR, Rothman-Denes LB, Salyers A, Schaechter M, Shapiro L, Silhavy TJ, Simon MI, Walker G, Yanofsky C, Zinder N.
Science
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Determination of the transcriptome of Vibrio cholerae during intraintestinal growth and midexponential phase in vitro.
Authors: Authors: Xu Q, Dziejman M, Mekalanos JJ.
Proc Natl Acad Sci U S A
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