John Mekalanos, PhD

Adele Lehman Professor of Microbiology and Molecular Genetics, Harvard Medical School
Antagonism toward the intestinal microbiota and its effect on Vibrio cholerae virulence.
Authors: Authors: Zhao W, Caro F, Robins W, Mekalanos JJ.
Science
View full abstract on Pubmed
Proteomic analysis of Vibrio cholerae outer membrane vesicles.
Authors: Authors: Altindis E, Fu Y, Mekalanos JJ.
Proc Natl Acad Sci U S A
View full abstract on Pubmed
MetR-regulated Vibrio cholerae metabolism is required for virulence.
Authors: Authors: Bogard RW, Davies BW, Mekalanos JJ.
mBio
View full abstract on Pubmed
The origin of the Haitian cholera outbreak strain.
Authors: Authors: Chin CS, Sorenson J, Harris JB, Robins WP, Charles RC, Jean-Charles RR, Bullard J, Webster DR, Kasarskis A, Peluso P, Paxinos EE, Yamaichi Y, Calderwood SB, Mekalanos JJ, Schadt EE, Waldor MK.
N Engl J Med
View full abstract on Pubmed
A defined transposon mutant library and its use in identifying motility genes in Vibrio cholerae.
Authors: Authors: Cameron DE, Urbach JM, Mekalanos JJ.
Proc Natl Acad Sci U S A
View full abstract on Pubmed
Transmissibility of cholera: in vivo-formed biofilms and their relationship to infectivity and persistence in the environment.
Authors: Authors: Faruque SM, Biswas K, Udden SM, Ahmad QS, Sack DA, Nair GB, Mekalanos JJ.
Proc Natl Acad Sci U S A
View full abstract on Pubmed
Genomic characterization of non-O1, non-O139 Vibrio cholerae reveals genes for a type III secretion system.
Authors: Authors: Dziejman M, Serruto D, Tam VC, Sturtevant D, Diraphat P, Faruque SM, Rahman MH, Heidelberg JF, Decker J, Li L, Montgomery KT, Grills G, Kucherlapati R, Mekalanos JJ.
Proc Natl Acad Sci U S A
View full abstract on Pubmed
Rapid genetic analysis of Helicobacter pylori gastric mucosal colonization in suckling mice.
Authors: Authors: Guo BP, Mekalanos JJ.
Proc Natl Acad Sci U S A
View full abstract on Pubmed
Construction of a Vibrio cholerae vaccine candidate using transposon delivery and FLP recombinase-mediated excision.
Authors: Authors: Chiang SL, Mekalanos JJ.
Infect Immun
View full abstract on Pubmed
In vivo genetic analysis of bacterial virulence.
Authors: Authors: Chiang SL, Mekalanos JJ, Holden DW.
Annu Rev Microbiol
View full abstract on Pubmed