John Mekalanos, PhD
Adele Lehman Professor of Microbiology and Molecular Genetics, Harvard Medical School
Gut check: testing a role for the intestinal microbiome in human obesity.
Genomic analysis of the Mozambique strain of Vibrio cholerae O1 reveals the origin of El Tor strains carrying classical CTX prophage.
Authors: Authors: Faruque SM, Tam VC, Chowdhury N, Diraphat P, Dziejman M, Heidelberg JF, Clemens JD, Mekalanos JJ, Nair GB.
Proc Natl Acad Sci U S A
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Proc Natl Acad Sci U S A
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Transcriptional profiling of Vibrio cholerae recovered directly from patient specimens during early and late stages of human infection.
Authors: Authors: Larocque RC, Harris JB, Dziejman M, Li X, Khan AI, Faruque AS, Faruque SM, Nair GB, Ryan ET, Qadri F, Mekalanos JJ, Calderwood SB.
Infect Immun
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Infect Immun
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Pathogenicity islands and phages in Vibrio cholerae evolution.
Clinical and environmental isolates of Vibrio cholerae serogroup O141 carry the CTX phage and the genes encoding the toxin-coregulated pili.
Authors: Authors: Dalsgaard A, Serichantalergs O, Forslund A, Lin W, Mekalanos J, Mintz E, Shimada T, Wells JG.
J Clin Microbiol
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J Clin Microbiol
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Lysogenic conversion of environmental Vibrio mimicus strains by CTXPhi.
Authors: Authors: Faruque SM, Rahman MM, Nasirul Islam KM, Mekalanos JJ.
Infect Immun
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Infect Immun
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Systematic identification of essential genes by in vitro mariner mutagenesis.
Authors: Authors: Akerley BJ, Rubin EJ, Camilli A, Lampe DJ, Robertson HM, Mekalanos JJ.
Proc Natl Acad Sci U S A
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Proc Natl Acad Sci U S A
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Lipoprotein e(P4) is essential for hemin uptake by Haemophilus influenzae.
Live bacterial vaccines: environmental aspects.
Repressor binding to a regulatory site in the DNA coding sequence is sufficient to confer transcriptional regulation of the vir-repressed genes (vrg genes) in Bordetella pertussis.