John Mekalanos, PhD

Adele Lehman Professor of Microbiology and Molecular Genetics, Harvard Medical School
Single amino acid substitutions in the N-terminus of Vibrio cholerae TcpA affect colonization, autoagglutination, and serum resistance.
Authors: Authors: Chiang SL, Taylor RK, Koomey M, Mekalanos JJ.
Mol Microbiol
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Live attenuated vaccine vectors.
Authors: Authors: Mekalanos JJ.
Int J Technol Assess Health Care
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Constitutive sensory transduction mutations in the Bordetella pertussis bvgS gene.
Authors: Authors: Miller JF, Johnson SA, Black WJ, Beattie DT, Mekalanos JJ, Falkow S.
J Bacteriol
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Salmonella vaccines with mutations in the phoP virulence regulon.
Authors: Authors: Miller SI, Mekalanos JJ, Pulkkinen WS.
Res Microbiol
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Evidence that glutamic acid 167 is an active-site residue of Shiga-like toxin I.
Authors: Authors: Hovde CJ, Calderwood SB, Mekalanos JJ, Collier RJ.
Proc Natl Acad Sci U S A
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Identification of a pilus colonization factor that is coordinately regulated with cholera toxin.
Authors: Authors: Taylor RK, Miller VL, Furlong DB, Mekalanos JJ.
Ann Sclavo Collana Monogr
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Enzymic activity of cholera toxin. I. New method of assay and the mechanism of ADP-ribosyl transfer.
Authors: Authors: Mekalanos JJ, Collier RJ, Romig WR.
J Biol Chem
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Protein covariance networks reveal interactions important to the emergence of SARS coronaviruses as human pathogens.
Authors: Authors: Robins WP, Mekalanos JJ.
bioRxiv
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Structure and mutagenic analysis of the lipid II flippase MurJ from Escherichia coli.
Authors: Authors: Zheng S, Sham LT, Rubino FA, Brock KP, Robins WP, Mekalanos JJ, Marks DS, Bernhardt TG, Kruse AC.
Proc Natl Acad Sci U S A
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RS1 satellite phage promotes diversity of toxigenic Vibrio cholerae by driving CTX prophage loss and elimination of lysogenic immunity.
Authors: Authors: Kamruzzaman M, Robins WP, Bari SM, Nahar S, Mekalanos JJ, Faruque SM.
Infect Immun
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