John Mekalanos, PhD

Adele Lehman Professor of Microbiology and Molecular Genetics, Harvard Medical School
Genetic mapping of Vibrio cholerae enterotoxin structural genes.
Authors: Authors: Sporecke I, Castro D, Mekalanos JJ.
J Bacteriol
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In vitro characterization and preclinical immunogenicity of Typhax, a typhoid fever protein capsular matrix vaccine candidate.
Authors: Authors: Griffin TJ, Thanawastien A, Cartee RT, Mekalanos JJ, Killeen KP.
Hum Vaccin Immunother
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Type VI secretion system sheaths as nanoparticles for antigen display.
Authors: Authors: Del Tordello E, Danilchanka O, McCluskey AJ, Mekalanos JJ.
Proc Natl Acad Sci U S A
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Enhanced in vivo fitness of carbapenem-resistant oprD mutants of Pseudomonas aeruginosa revealed through high-throughput sequencing.
Authors: Authors: Skurnik D, Roux D, Cattoir V, Danilchanka O, Lu X, Yoder-Himes DR, Han K, Guillard T, Jiang D, Gaultier C, Guerin F, Aschard H, Leclercq R, Mekalanos JJ, Lory S, Pier GB.
Proc Natl Acad Sci U S A
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Type VI secretion requires a dynamic contractile phage tail-like structure.
Authors: Authors: Basler M, Pilhofer M, Henderson GP, Jensen GJ, Mekalanos JJ.
Nature
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In vivo actin cross-linking induced by Vibrio cholerae type VI secretion system is associated with intestinal inflammation.
Authors: Authors: Ma AT, Mekalanos JJ.
Proc Natl Acad Sci U S A
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Threonine phosphorylation post-translationally regulates protein secretion in Pseudomonas aeruginosa.
Authors: Authors: Mougous JD, Gifford CA, Ramsdell TL, Mekalanos JJ.
Nat Cell Biol
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Bile acids stimulate biofilm formation in Vibrio cholerae.
Authors: Authors: Hung DT, Zhu J, Sturtevant D, Mekalanos JJ.
Mol Microbiol
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The opportunistic pathogen Pseudomonas aeruginosa carries a secretable arachidonate 15-lipoxygenase.
Authors: Authors: Vance RE, Hong S, Gronert K, Serhan CN, Mekalanos JJ.
Proc Natl Acad Sci U S A
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A genome-scale analysis for identification of genes required for growth or survival of Haemophilus influenzae.
Authors: Authors: Akerley BJ, Rubin EJ, Novick VL, Amaya K, Judson N, Mekalanos JJ.
Proc Natl Acad Sci U S A
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