John Mekalanos, PhD

Adele Lehman Professor of Microbiology and Molecular Genetics, Harvard Medical School
Construction of a Vibrio cholerae vaccine candidate using transposon delivery and FLP recombinase-mediated excision.
Authors: Authors: Chiang SL, Mekalanos JJ.
Infect Immun
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In vivo genetic analysis of bacterial virulence.
Authors: Authors: Chiang SL, Mekalanos JJ, Holden DW.
Annu Rev Microbiol
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Cholera: molecular basis for emergence and pathogenesis.
Authors: Authors: Mekalanos JJ, Rubin EJ, Waldor MK.
FEMS Immunol Med Microbiol
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Analysis of Vibrio cholerae ToxR function by construction of novel fusion proteins.
Authors: Authors: Ottemann KM, Mekalanos JJ.
Mol Microbiol
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Monoclonal immunoglobulin A antibodies directed against cholera toxin prevent the toxin-induced chloride secretory response and block toxin binding to intestinal epithelial cells in vitro.
Authors: Authors: Apter FM, Lencer WI, Finkelstein RA, Mekalanos JJ, Neutra MR.
Infect Immun
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Bacterial mucosal vaccines.
Authors: Authors: Mekalanos JJ.
Adv Exp Med Biol
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Identification of a bacteriophage containing a silent staphylococcal variant enterotoxin gene (sezA+).
Authors: Authors: Soltis MT, Mekalanos JJ, Betley MJ.
Infect Immun
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Confirmation of the Fur operator site by insertion of a synthetic oligonucleotide into an operon fusion plasmid.
Authors: Authors: Calderwood SB, Mekalanos JJ.
J Bacteriol
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Genetic analysis of the cholera toxin-positive regulatory gene toxR.
Authors: Authors: Miller VL, Mekalanos JJ.
J Bacteriol
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Affinity filters, a new approach to the isolation of tox mutants of Vibrio cholerae.
Authors: Authors: Mekalanos JJ, Collier RJ, Romig WR.
Proc Natl Acad Sci U S A
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