Jon Clardy, PhD

Hsien Wu and Daisy Yen Wu Professor of Biological Chemistry and Molecular Pharmacology, Harvard Medical School
Discovery of a novel pharmacological and structural class of gamma secretase modulators derived from the extract of Actaea racemosa.
Authors: Authors: Findeis MA, Schroeder F, McKee TD, Yager D, Fraering PC, Creaser SP, Austin WF, Clardy J, Wang R, Selkoe D, Eckman CB.
ACS Chem Neurosci
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Roseobacticides: small molecule modulators of an algal-bacterial symbiosis.
Authors: Authors: Seyedsayamdost MR, Carr G, Kolter R, Clardy J.
J Am Chem Soc
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Crystal and solution structures of an odorant-binding protein from the southern house mosquito complexed with an oviposition pheromone.
Authors: Authors: Mao Y, Xu X, Xu W, Ishida Y, Leal WS, Ames JB, Clardy J.
Proc Natl Acad Sci U S A
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Regulating alternative lifestyles in entomopathogenic bacteria.
Authors: Authors: Crawford JM, Kontnik R, Clardy J.
Curr Biol
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Dentigerumycin: a bacterial mediator of an ant-fungus symbiosis.
Authors: Authors: Oh DC, Poulsen M, Currie CR, Clardy J.
Nat Chem Biol
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Citral sensing by Transient [corrected] receptor potential channels in dorsal root ganglion neurons.
Authors: Authors: Stotz SC, Vriens J, Martyn D, Clardy J, Clapham DE.
PLoS One
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Gene expression signature-based chemical genomic prediction identifies a novel class of HSP90 pathway modulators.
Authors: Authors: Hieronymus H, Lamb J, Ross KN, Peng XP, Clement C, Rodina A, Nieto M, Du J, Stegmaier K, Raj SM, Maloney KN, Clardy J, Hahn WC, Chiosis G, Golub TR.
Cancer Cell
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N-acyl derivatives of arginine and tryptophan isolated from environmental DNA expressed in Escherichia coli.
Authors: Authors: Brady SF, Clardy J.
Org Lett
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Trichodermamides A and B, cytotoxic modified dipeptides from the marine-derived fungus Trichoderma virens.
Authors: Authors: Garo E, Starks CM, Jensen PR, Fenical W, Lobkovsky E, Clardy J.
J Nat Prod
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Dicerandrols, new antibiotic and cytotoxic dimers produced by the fungus Phomopsis longicolla isolated from an endangered mint.
Authors: Authors: Wagenaar MM, Clardy J.
J Nat Prod
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