Jon Clardy, PhD

Hsien Wu and Daisy Yen Wu Professor of Biological Chemistry and Molecular Pharmacology, Harvard Medical School
A Rebeccamycin Analog Provides Plasmid-Encoded Niche Defense.
Authors: Authors: Van Arnam EB, Ruzzini AC, Sit CS, Currie CR, Clardy J.
J Am Chem Soc
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Chemical interrogation of the malaria kinome.
Authors: Authors: Derbyshire ER, Zuzarte-Luís V, Magalhães AD, Kato N, Sanschagrin PC, Wang J, Zhou W, Miduturu CV, Mazitschek R, Sliz P, Mota MM, Gray NS, Clardy J.
Chembiochem
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Identification of anziaic acid, a lichen depside from Hypotrachyna sp., as a new topoisomerase poison inhibitor.
Authors: Authors: Cheng B, Cao S, Vasquez V, Annamalai T, Tamayo-Castillo G, Clardy J, Tse-Dinh YC.
PLoS One
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A Bacillus subtilis sensor kinase involved in triggering biofilm formation on the roots of tomato plants.
Authors: Authors: Chen Y, Cao S, Chai Y, Clardy J, Kolter R, Guo JH, Losick R.
Mol Microbiol
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Heavy metal and pesticide content in commonly prescribed individual raw Chinese Herbal Medicines.
Authors: Authors: Harris ES, Cao S, Littlefield BA, Craycroft JA, Scholten R, Kaptchuk T, Fu Y, Wang W, Liu Y, Chen H, Zhao Z, Clardy J, Woolf AD, Eisenberg DM.
Sci Total Environ
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A concise silylamine approach to 2-amino-3-hydroxy-indoles with potent in vivo antimalaria activity.
Authors: Authors: Urgaonkar S, Cortese JF, Barker RH, Cromwell M, Serrano AE, Wirth DF, Clardy J, Mazitschek R.
Org Lett
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Antiplasmodial activity of piperazine sulfonamides.
Authors: Authors: Martyn DC, Cortese JF, Tyndall E, Dick J, Mazitschek R, Munoz B, Clardy J.
Bioorg Med Chem Lett
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Biosynthesis of the Caenorhabditis elegans dauer pheromone.
Authors: Authors: Butcher RA, Ragains JR, Li W, Ruvkun G, Clardy J, Mak HY.
Proc Natl Acad Sci U S A
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Detecting binding interactions using microarrays of natural product extracts.
Authors: Authors: Schmitz K, Haggarty SJ, McPherson OM, Clardy J, Koehler AN.
J Am Chem Soc
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Bisandrographolide from Andrographis paniculata activates TRPV4 channels.
Authors: Authors: Smith PL, Maloney KN, Pothen RG, Clardy J, Clapham DE.
J Biol Chem
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