Jon Clardy, PhD

Hsien Wu and Daisy Yen Wu Professor of Biological Chemistry and Molecular Pharmacology, Harvard Medical School
Microbial community modulates growth of symbiotic fungus required for stingless bee metamorphosis.
Authors: Authors: Paludo CR, Pishchany G, Andrade-Dominguez A, Silva-Junior EA, Menezes C, Nascimento FS, Currie CR, Kolter R, Clardy J, Pupo MT.
PLoS One
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Oridonin inhibits aberrant AKT activation in breast cancer.
Authors: Authors: Sun B, Wang G, Liu H, Liu P, Twal WO, Cheung H, Carroll SL, Ethier SP, Mevers EE, Clardy J, Roberts T, Chen C, Li Q, Wang L, Yang M, Zhao JJ, Wang Q.
Oncotarget
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Chemical warfare: The battle between termite-associated actinobacteria and Trichoderma harzianum, a fungal pathogen.
Authors: Authors: Mevers E, Saurí J, Moser A, Varlan M, Martin GE, Clardy JC.
Planta Med
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Isolation and Synthesis of a Bacterially Produced Inhibitor of Rosette Development in Choanoflagellates.
Authors: Authors: Cantley AM, Woznica A, Beemelmanns C, King N, Clardy J.
J Am Chem Soc
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A new antibacterial octaketide and cytotoxic phenylethanoid glycosides from Pogostemon cablin (Blanco) Benth.
Authors: Authors: Kim KH, Beemelmanns C, Clardy J, Cao S.
Bioorg Med Chem Lett
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Bacterial symbionts in agricultural systems provide a strategic source for antibiotic discovery.
Authors: Authors: Ramadhar TR, Beemelmanns C, Currie CR, Clardy J.
J Antibiot (Tokyo)
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Protein evolution: when two become three.
Authors: Authors: Stallforth P, Clardy J.
Curr Biol
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Identification and validation of tetracyclic benzothiazepines as Plasmodium falciparum cytochrome bc1 inhibitors.
Authors: Authors: Dong CK, Urgaonkar S, Cortese JF, Gamo FJ, Garcia-Bustos JF, Lafuente MJ, Patel V, Ross L, Coleman BI, Derbyshire ER, Clish CB, Serrano AE, Cromwell M, Barker RH, Dvorin JD, Duraisingh MT, Wirth DF, Clardy J, Mazitschek R.
Chem Biol
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Sceliphrolactam, a polyene macrocyclic lactam from a wasp-associated Streptomyces sp.
Authors: Authors: Oh DC, Poulsen M, Currie CR, Clardy J.
Org Lett
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A non-radioactive DAPI-based high-throughput in vitro assay to assess Plasmodium falciparum responsiveness to antimalarials--increased sensitivity of P. falciparum to chloroquine in Senegal.
Authors: Authors: Ndiaye D, Patel V, Demas A, LeRoux M, Ndir O, Mboup S, Clardy J, Lakshmanan V, Daily JP, Wirth DF.
Am J Trop Med Hyg
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