Jon Clardy, PhD
Hsien Wu and Daisy Yen Wu Professor of Biological Chemistry and Molecular Pharmacology, Harvard Medical School
A limonoid antifeedant from seed of Carapa procera.
Authors: Authors: Mikolajczak KL, Weisleder D, Parkanyi L, Clardy J.
J Nat Prod
View full abstract on Pubmed
J Nat Prod
View full abstract on Pubmed
Austin, a novel polyisoprenoid mycotoxin from Aspergillus ustus.
Authors: Authors: Chexal KK, Spinger JP, Clardy J, Cole RJ, Kirksey JW, Dorner JW, Cutler HG, Strawter BJ.
J Am Chem Soc
View full abstract on Pubmed
J Am Chem Soc
View full abstract on Pubmed
A conserved coccidian gene is involved in Toxoplasma sensitivity to the anti-apicomplexan compound, tartrolon E.
Authors: Authors: Bowden GD, Reis PM, Rogers MB, Bone Relat RM, Brayton KA, Wilson SK, Di Genova BM, Knoll LJ, Nepveux V FJ, Tai AK, Ramadhar TR, Clardy J, O'Connor RM.
Int J Parasitol Drugs Drug Resist
View full abstract on Pubmed
Int J Parasitol Drugs Drug Resist
View full abstract on Pubmed
Amycomicin is a potent and specific antibiotic discovered with a targeted interaction screen.
Authors: Authors: Pishchany G, Mevers E, Ndousse-Fetter S, Horvath DJ, Paludo CR, Silva-Junior EA, Koren S, Skaar EP, Clardy J, Kolter R.
Proc Natl Acad Sci U S A
View full abstract on Pubmed
Proc Natl Acad Sci U S A
View full abstract on Pubmed
The Neuroprotective Marine Compound Psammaplysene A Binds the RNA-Binding Protein HNRNPK.
Authors: Authors: Boccitto M, Lee N, Sakamoto S, Spruce LA, Handa H, Clardy J, Seeholzer SH, Kalb RG.
Mar Drugs
View full abstract on Pubmed
Mar Drugs
View full abstract on Pubmed
Genome Sequence of Streptomyces sp. Strain RTd22, an Endophyte of the Mexican Sunflower.
Authors: Authors: Chagas FO, Ruzzini AC, Bacha LV, Samborskyy M, Conti R, Pessotti RC, de Oliveira LG, Clardy J, Pupo MT.
Genome Announc
View full abstract on Pubmed
Genome Announc
View full abstract on Pubmed
Minimum Information about a Biosynthetic Gene cluster.
Authors: Authors: Medema MH, Kottmann R, Yilmaz P, Cummings M, Biggins JB, Blin K, de Bruijn I, Chooi YH, Claesen J, Coates RC, Cruz-Morales P, Duddela S, Düsterhus S, Edwards DJ, Fewer DP, Garg N, Geiger C, Gomez-Escribano JP, Greule A, Hadjithomas M, Haines AS, Helfrich EJ, Hillwig ML, Ishida K, Jones AC, Jones CS, Jungmann K, Kegler C, Kim HU, Kötter P, Krug D, Masschelein J, Melnik AV, Mantovani SM, Monroe EA, Moore M, Moss N, Nützmann HW, Pan G, Pati A, Petras D, Reen FJ, Rosconi F, Rui Z, Tian Z, Tobias NJ, Tsunematsu Y, Wiemann P, Wyckoff E, Yan X, Yim G, Yu F, Xie Y, Aigle B, Apel AK, Balibar CJ, Balskus EP, Barona-Gómez F, Bechthold A, Bode HB, Borriss R, Brady SF, Brakhage AA, Caffrey P, Cheng YQ, Clardy J, Cox RJ, De Mot R, Donadio S, Donia MS, van der Donk WA, Dorrestein PC, Doyle S, Driessen AJ, Ehling-Schulz M, Entian KD, Fischbach MA, Gerwick L, Gerwick WH, Gross H, Gust B, Hertweck C, Höfte M, Jensen SE, Ju J, Katz L, Kaysser L, Klassen JL, Keller NP, Kormanec J, Kuipers OP, Kuzuyama T, Kyrpides NC, Kwon HJ, Lautru S, Lavigne R, Lee CY, Linquan B, Liu X, Liu W, Luzhetskyy A, Mahmud T, Mast Y, Méndez C, Metsä-Ketelä M, Micklefield J, Mitchell DA, Moore BS, Moreira LM, Müller R, Neilan BA, Nett M, Nielsen J, O'Gara F, Oikawa H, Osbourn A, Osburne MS, Ostash B, Payne SM, Pernodet JL, Petricek M, Piel J, Ploux O, Raaijmakers JM, Salas JA, Schmitt EK, Scott B, Seipke RF, Shen B, Sherman DH, Sivonen K, Smanski MJ, Sosio M, Stegmann E, Süssmuth RD, Tahlan K, Thomas CM, Tang Y, Truman AW, Viaud M, Walton JD, Walsh CT, Weber T, van Wezel GP, Wilkinson B, Willey JM, Wohlleben W, Wright GD, Ziemert N, Zhang C, Zotchev SB, Breitling R, Takano E, Glöckner FO.
Nat Chem Biol
View full abstract on Pubmed
Nat Chem Biol
View full abstract on Pubmed
Insights into secondary metabolism from a global analysis of prokaryotic biosynthetic gene clusters.
Authors: Authors: Cimermancic P, Medema MH, Claesen J, Kurita K, Wieland Brown LC, Mavrommatis K, Pati A, Godfrey PA, Koehrsen M, Clardy J, Birren BW, Takano E, Sali A, Linington RG, Fischbach MA.
Cell
View full abstract on Pubmed
Cell
View full abstract on Pubmed
Synthesis and activity of biomimetic biofilm disruptors.
Authors: Authors: Böttcher T, Kolodkin-Gal I, Kolter R, Losick R, Clardy J.
J Am Chem Soc
View full abstract on Pubmed
J Am Chem Soc
View full abstract on Pubmed
Liver-stage malaria parasites vulnerable to diverse chemical scaffolds.
Authors: Authors: Derbyshire ER, Prudêncio M, Mota MM, Clardy J.
Proc Natl Acad Sci U S A
View full abstract on Pubmed
Proc Natl Acad Sci U S A
View full abstract on Pubmed