Jon Clardy, PhD

Hsien Wu and Daisy Yen Wu Professor of Biological Chemistry and Molecular Pharmacology, Harvard Medical School
A sexually conditioned switch of chemosensory behavior in C. elegans.
Authors: Authors: Sakai N, Iwata R, Yokoi S, Butcher RA, Clardy J, Tomioka M, Iino Y.
PLoS One
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Phenolic compounds as antiangiogenic CMG2 inhibitors from Costa Rican endophytic fungi.
Authors: Authors: Cao S, Cryan L, Habeshian KA, Murillo C, Tamayo-Castillo G, Rogers MS, Clardy J.
Bioorg Med Chem Lett
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The next opportunity in anti-malaria drug discovery: the liver stage.
Authors: Authors: Derbyshire ER, Mota MM, Clardy J.
PLoS Pathog
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Asterogynins: secondary metabolites from a Costa Rican endophytic fungus.
Authors: Authors: Cao S, Ross L, Tamayo G, Clardy J.
Org Lett
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Bionectriol A, a polyketide glycoside from the fungus Bionectria sp. associated with the fungus-growing ant, Apterostigma dentigerum.
Authors: Authors: Freinkman E, Oh DC, Scott JJ, Currie CR, Clardy J.
Tetrahedron Lett
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Progestins activate the AKT pathway in leiomyoma cells and promote survival.
Authors: Authors: Hoekstra AV, Sefton EC, Berry E, Lu Z, Hardt J, Marsh E, Yin P, Clardy J, Chakravarti D, Bulun S, Kim JJ.
J Clin Endocrinol Metab
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The evolution of gene collectives: How natural selection drives chemical innovation.
Authors: Authors: Fischbach MA, Walsh CT, Clardy J.
Proc Natl Acad Sci U S A
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FeeM, an N-acyl amino acid synthase from an uncultured soil microbe: structure, mechanism, and acyl carrier protein binding.
Authors: Authors: Van Wagoner RM, Clardy J.
Structure
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The psammaplysenes, specific inhibitors of FOXO1a nuclear export.
Authors: Authors: Schroeder FC, Kau TR, Silver PA, Clardy J.
J Nat Prod
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Synthesis of long-chain fatty acid enol esters isolated from an environmental DNA clone.
Authors: Authors: Brady SF, Clardy J.
Org Lett
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