Jon Clardy, PhD

Hsien Wu and Daisy Yen Wu Professor of Biological Chemistry and Molecular Pharmacology, Harvard Medical School
Pharbinilic acid, an allogibberic acid from morning glory (Pharbitis nil).
Authors: Authors: Kim KH, Choi SU, Son MW, Choi SZ, Clardy J, Lee KR.
J Nat Prod
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A single promoter inversion switches Photorhabdus between pathogenic and mutualistic states.
Authors: Authors: Somvanshi VS, Sloup RE, Crawford JM, Martin AR, Heidt AJ, Kim KS, Clardy J, Ciche TA.
Science
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NRPS substrate promiscuity diversifies the xenematides.
Authors: Authors: Crawford JM, Portmann C, Kontnik R, Walsh CT, Clardy J.
Org Lett
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Biosynthesis: not just passing through.
Authors: Authors: Crawford JM, Clardy J.
Nat Chem
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The ATP-dependent amide ligases DdaG and DdaF assemble the fumaramoyl-dipeptide scaffold of the dapdiamide antibiotics.
Authors: Authors: Hollenhorst MA, Clardy J, Walsh CT.
Biochemistry
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Mycangimycin, a polyene peroxide from a mutualist Streptomyces sp.
Authors: Authors: Oh DC, Scott JJ, Currie CR, Clardy J.
Org Lett
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Synthetic libraries of tyrosine-derived bacterial metabolites.
Authors: Authors: Georgiades SN, Clardy J.
Bioorg Med Chem Lett
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Phaeosphaeride A, an inhibitor of STAT3-dependent signaling isolated from an endophytic fungus.
Authors: Authors: Maloney KN, Hao W, Xu J, Gibbons J, Hucul J, Roll D, Brady SF, Schroeder FC, Clardy J.
Org Lett
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Lessons from natural molecules.
Authors: Authors: Clardy J, Walsh C.
Nature
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Structure of the large FK506-binding protein FKBP51, an Hsp90-binding protein and a component of steroid receptor complexes.
Authors: Authors: Sinars CR, Cheung-Flynn J, Rimerman RA, Scammell JG, Smith DF, Clardy J.
Proc Natl Acad Sci U S A
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