Jon Clardy, PhD

Hsien Wu and Daisy Yen Wu Professor of Biological Chemistry and Molecular Pharmacology, Harvard Medical School
A chemical genetic screen identifies inhibitors of regulated nuclear export of a Forkhead transcription factor in PTEN-deficient tumor cells.
Authors: Authors: Kau TR, Schroeder F, Ramaswamy S, Wojciechowski CL, Zhao JJ, Roberts TM, Clardy J, Sellers WR, Silver PA.
Cancer Cell
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Akanthomycin, a new antibiotic pyridone from the entomopathogenic fungus Akanthomyces gracilis.
Authors: Authors: Wagenaar MM, Gibson DM, Clardy J.
Org Lett
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Structural basis for the insensitivity of a serine enzyme (palmitoyl-protein thioesterase) to phenylmethylsulfonyl fluoride.
Authors: Authors: Das AK, Bellizzi JJ, Tandel S, Biehl E, Clardy J, Hofmann SL.
J Biol Chem
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Crystallization and preliminary X-ray crystallographic analysis of the Pseudomonas aeruginosa cyclohexadienyl dehydratase.
Authors: Authors: Kongsaeree P, Liang J, Jensen RA, Clardy J.
Acta Crystallogr D Biol Crystallogr
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Comparison of the structures of the cyclotheonamide A complexes of human alpha-thrombin and bovine beta-trypsin.
Authors: Authors: Ganesh V, Lee AY, Clardy J, Tulinsky A.
Protein Sci
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A pentahalogenated monoterpene from the red alga Portieria hornemannii produces a novel cytotoxicity profile against a diverse panel of human tumor cell lines.
Authors: Authors: Fuller RW, Cardellina JH, Kato Y, Brinen LS, Clardy J, Snader KM, Boyd MR.
J Med Chem
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Pentacyclo[12.2.2.22,5.26,9.210,13]-1,5,9,13-tetracosatetraene and its reaction with silver trifluoromethanesulfonate. Synthesis of a square-planar d10 organometallic complex.
Authors: Authors: McMurry JE, Haley GJ, Matz JR, Clardy JC, Mitchell J.
J Am Chem Soc
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Letter: Structure and synthesis of verruculotoxin, a new mycotoxin from Penicillium verruculosum Peyronel.
Authors: Authors: Macmillan JG, Springer JP, Clardy J, Cole RJ, Kirksey JW.
J Am Chem Soc
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Molecular messages in human microbiota.
Authors: Authors: Henke MT, Clardy J.
Science
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Discovery of Antimicrobial Lipodepsipeptides Produced by a Serratia sp. within Mosquito Microbiomes.
Authors: Authors: Ganley JG, Carr G, Ioerger TR, Sacchettini JC, Clardy J, Derbyshire ER.
Chembiochem
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