Jon Clardy, PhD

Hsien Wu and Daisy Yen Wu Professor of Biological Chemistry and Molecular Pharmacology, Harvard Medical School
GABA-modulating bacteria of the human gut microbiota.
Authors: Authors: Strandwitz P, Kim KH, Terekhova D, Liu JK, Sharma A, Levering J, McDonald D, Dietrich D, Ramadhar TR, Lekbua A, Mroue N, Liston C, Stewart EJ, Dubin MJ, Zengler K, Knight R, Gilbert JA, Clardy J, Lewis K.
Nat Microbiol
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Lysophosphatidylcholine Regulates Sexual Stage Differentiation in the Human Malaria Parasite Plasmodium falciparum.
Authors: Authors: Brancucci NMB, Gerdt JP, Wang C, De Niz M, Philip N, Adapa SR, Zhang M, Hitz E, Niederwieser I, Boltryk SD, Laffitte MC, Clark MA, Grüring C, Ravel D, Blancke Soares A, Demas A, Bopp S, Rubio-Ruiz B, Conejo-Garcia A, Wirth DF, Gendaszewska-Darmach E, Duraisingh MT, Adams JH, Voss TS, Waters AP, Jiang RHY, Clardy J, Marti M.
Cell
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Compounds that select against the tetracycline-resistance efflux pump.
Authors: Authors: Stone LK, Baym M, Lieberman TD, Chait R, Clardy J, Kishony R.
Nat Chem Biol
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Genome Sequences of Three Pseudoalteromonas Strains (P1-8, P1-11, and P1-30), Isolated from the Marine Hydroid Hydractinia echinata.
Authors: Authors: Klassen JL, Rischer M, Wolf T, Guo H, Shelest E, Clardy J, Beemelmanns C.
Genome Announc
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A systematic analysis of biosynthetic gene clusters in the human microbiome reveals a common family of antibiotics.
Authors: Authors: Donia MS, Cimermancic P, Schulze CJ, Wieland Brown LC, Martin J, Mitreva M, Clardy J, Linington RG, Fischbach MA.
Cell
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Pharbinilic acid, an allogibberic acid from morning glory (Pharbitis nil).
Authors: Authors: Kim KH, Choi SU, Son MW, Choi SZ, Clardy J, Lee KR.
J Nat Prod
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A single promoter inversion switches Photorhabdus between pathogenic and mutualistic states.
Authors: Authors: Somvanshi VS, Sloup RE, Crawford JM, Martin AR, Heidt AJ, Kim KS, Clardy J, Ciche TA.
Science
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NRPS substrate promiscuity diversifies the xenematides.
Authors: Authors: Crawford JM, Portmann C, Kontnik R, Walsh CT, Clardy J.
Org Lett
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Biosynthesis: not just passing through.
Authors: Authors: Crawford JM, Clardy J.
Nat Chem
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The ATP-dependent amide ligases DdaG and DdaF assemble the fumaramoyl-dipeptide scaffold of the dapdiamide antibiotics.
Authors: Authors: Hollenhorst MA, Clardy J, Walsh CT.
Biochemistry
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