Junying Yuan, PhD

Elizabeth D. Hay Professor of Cell Biology, Harvard Medical School
Structure-activity relationship and liver microsome stability studies of pyrrole necroptosis inhibitors.
Authors: Authors: Teng X, Keys H, Yuan J, Degterev A, Cuny GD.
Bioorg Med Chem Lett
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Regulation of intracellular accumulation of mutant Huntingtin by Beclin 1.
Authors: Authors: Shibata M, Lu T, Furuya T, Degterev A, Mizushima N, Yoshimori T, MacDonald M, Yankner B, Yuan J.
J Biol Chem
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The PHD finger of the chromatin-associated protein ING2 functions as a nuclear phosphoinositide receptor.
Authors: Authors: Gozani O, Karuman P, Jones DR, Ivanov D, Cha J, Lugovskoy AA, Baird CL, Zhu H, Field SJ, Lessnick SL, Villasenor J, Mehrotra B, Chen J, Rao VR, Brugge JS, Ferguson CG, Payrastre B, Myszka DG, Cantley LC, Wagner G, Divecha N, Prestwich GD, Yuan J.
Cell
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Flightless-I regulates proinflammatory caspases by selectively modulating intracellular localization and caspase activity.
Authors: Authors: Li J, Yin HL, Yuan J.
J Cell Biol
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Pten deficiency activates distinct downstream signaling pathways in a tissue-specific manner.
Authors: Authors: Yoo LI, Liu DW, Le Vu S, Bronson RT, Wu H, Yuan J.
Cancer Res
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Bax and Bak can localize to the endoplasmic reticulum to initiate apoptosis.
Authors: Authors: Zong WX, Li C, Hatzivassiliou G, Lindsten T, Yu QC, Yuan J, Thompson CB.
J Cell Biol
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Inducing autophagy harmlessly.
Authors: Authors: Yuan J.
Autophagy
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Structure-activity relationship study of novel necroptosis inhibitors.
Authors: Authors: Teng X, Degterev A, Jagtap P, Xing X, Choi S, Denu R, Yuan J, Cuny GD.
Bioorg Med Chem Lett
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Dissociation between neurodegeneration and caspase-11-mediated activation of caspase-1 and caspase-3 in a mouse model of amyotrophic lateral sclerosis.
Authors: Authors: Kang SJ, Sanchez I, Jing N, Yuan J.
J Neurosci
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c-IAP1 cooperates with Myc by acting as a ubiquitin ligase for Mad1.
Authors: Authors: Xu L, Zhu J, Hu X, Zhu H, Kim HT, LaBaer J, Goldberg A, Yuan J.
Mol Cell
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