Junying Yuan, PhD
Elizabeth D. Hay Professor of Cell Biology, Harvard Medical School
Activation of PI3K/Akt and MAPK pathways regulates Myc-mediated transcription by phosphorylating and promoting the degradation of Mad1.
Coordinated expression of caspase 8, 3 and 7 mRNA in temporal cortex of Alzheimer disease: relationship to formic acid extractable abeta42 levels.
Authors: Authors: Matsui T, Ramasamy K, Ingelsson M, Fukumoto H, Conrad C, Frosch MP, Irizarry MC, Yuan J, Hyman BT.
J Neuropathol Exp Neurol
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J Neuropathol Exp Neurol
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Alpha-synuclein oligomerization: a role for lipids?
Structure-activity relationship and liver microsome stability studies of pyrrole necroptosis inhibitors.
Authors: Authors: Teng X, Keys H, Yuan J, Degterev A, Cuny GD.
Bioorg Med Chem Lett
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Bioorg Med Chem Lett
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Regulation of intracellular accumulation of mutant Huntingtin by Beclin 1.
Authors: Authors: Shibata M, Lu T, Furuya T, Degterev A, Mizushima N, Yoshimori T, MacDonald M, Yankner B, Yuan J.
J Biol Chem
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J Biol Chem
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The PHD finger of the chromatin-associated protein ING2 functions as a nuclear phosphoinositide receptor.
Authors: Authors: Gozani O, Karuman P, Jones DR, Ivanov D, Cha J, Lugovskoy AA, Baird CL, Zhu H, Field SJ, Lessnick SL, Villasenor J, Mehrotra B, Chen J, Rao VR, Brugge JS, Ferguson CG, Payrastre B, Myszka DG, Cantley LC, Wagner G, Divecha N, Prestwich GD, Yuan J.
Cell
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Cell
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Flightless-I regulates proinflammatory caspases by selectively modulating intracellular localization and caspase activity.
Pten deficiency activates distinct downstream signaling pathways in a tissue-specific manner.
Authors: Authors: Yoo LI, Liu DW, Le Vu S, Bronson RT, Wu H, Yuan J.
Cancer Res
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Cancer Res
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Bax and Bak can localize to the endoplasmic reticulum to initiate apoptosis.
Authors: Authors: Zong WX, Li C, Hatzivassiliou G, Lindsten T, Yu QC, Yuan J, Thompson CB.
J Cell Biol
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J Cell Biol
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Inducing autophagy harmlessly.