Junying Yuan, PhD

Elizabeth D. Hay Professor of Cell Biology, Harvard Medical School
Activation of PI3K/Akt and MAPK pathways regulates Myc-mediated transcription by phosphorylating and promoting the degradation of Mad1.
Authors: Authors: Zhu J, Blenis J, Yuan J.
Proc Natl Acad Sci U S A
View full abstract on Pubmed
Coordinated expression of caspase 8, 3 and 7 mRNA in temporal cortex of Alzheimer disease: relationship to formic acid extractable abeta42 levels.
Authors: Authors: Matsui T, Ramasamy K, Ingelsson M, Fukumoto H, Conrad C, Frosch MP, Irizarry MC, Yuan J, Hyman BT.
J Neuropathol Exp Neurol
View full abstract on Pubmed
Alpha-synuclein oligomerization: a role for lipids?
Authors: Authors: Welch K, Yuan J.
Trends Neurosci
View full abstract on Pubmed
Structure-activity relationship and liver microsome stability studies of pyrrole necroptosis inhibitors.
Authors: Authors: Teng X, Keys H, Yuan J, Degterev A, Cuny GD.
Bioorg Med Chem Lett
View full abstract on Pubmed
Regulation of intracellular accumulation of mutant Huntingtin by Beclin 1.
Authors: Authors: Shibata M, Lu T, Furuya T, Degterev A, Mizushima N, Yoshimori T, MacDonald M, Yankner B, Yuan J.
J Biol Chem
View full abstract on Pubmed
The PHD finger of the chromatin-associated protein ING2 functions as a nuclear phosphoinositide receptor.
Authors: Authors: Gozani O, Karuman P, Jones DR, Ivanov D, Cha J, Lugovskoy AA, Baird CL, Zhu H, Field SJ, Lessnick SL, Villasenor J, Mehrotra B, Chen J, Rao VR, Brugge JS, Ferguson CG, Payrastre B, Myszka DG, Cantley LC, Wagner G, Divecha N, Prestwich GD, Yuan J.
Cell
View full abstract on Pubmed
Flightless-I regulates proinflammatory caspases by selectively modulating intracellular localization and caspase activity.
Authors: Authors: Li J, Yin HL, Yuan J.
J Cell Biol
View full abstract on Pubmed
Pten deficiency activates distinct downstream signaling pathways in a tissue-specific manner.
Authors: Authors: Yoo LI, Liu DW, Le Vu S, Bronson RT, Wu H, Yuan J.
Cancer Res
View full abstract on Pubmed
Bax and Bak can localize to the endoplasmic reticulum to initiate apoptosis.
Authors: Authors: Zong WX, Li C, Hatzivassiliou G, Lindsten T, Yu QC, Yuan J, Thompson CB.
J Cell Biol
View full abstract on Pubmed
Inducing autophagy harmlessly.
Authors: Authors: Yuan J.
Autophagy
View full abstract on Pubmed